Results 101 to 110 of about 390,946 (318)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Erupción fija por luz solar, una serie de 13 casos en Bogotá, Colombia
Actas Dermo-SifiliográficasResumen: Desde 1975 se han publicado algunos casos que asocian la radiación ultravioleta como un desencadenante de erupciones cutáneas fijas (erupción o exantema fijo por luz solar o síndrome de fotosensibilidad localizada de amplio espectro ...
M.C. Valbuena +2 more
doaj
Drug Hepatotoxicity: Environmental Factors [PDF]
, 2017 Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
A case of imipramine-associated immune thrombocytopenia
The Turkish Journal of Pediatrics, 2009 Drug-induced immune thrombocytopenia (DITP), excluding heparin-induced thrombocytopenia, is relatively uncommon. It is characterized by drug-dependent antibodies that bind to the platelets and cause their destruction when the responsible drug is ...
Ayşe Aksoy, Erol Erduran, Yusuf Gedik
doaj
Tubulointerstitial Nephritis and Uveitis Syndrome: Are Drugs Offenders or Bystanders?
Clinical Medicine Insights: Case Reports, 2016 A 16-year-old female patient was admitted to our hospital due to progressive renal dysfunction with an increased serum creatinine (sCr) level of 1.7 mg/dL.
Mutsumi Kawamata +9 more
doaj +1 more source
Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]
, 2016 ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph +5 more
core +1 more source
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
An Investigation of the Risk Factors Associated With Anti-Tuberculosis Drug-Induced Liver Injury or Abnormal Liver Functioning in 757 Patients With Pulmonary Tuberculosis [PDF]
, 2021 Tao Zhong +7 more
openalex +1 more source
Cocaine Self-Administration Experience Induces Pathological Phasic Accumbens Dopamine Signals and Abnormal Incentive Behaviors in Drug-Abstinent Rats [PDF]
, 2016 Michael P. Saddoris +3 more
openalex +3 more sources