Results 21 to 30 of about 449,868 (304)

Unlocking the potential of anti-CD33 therapy in adult and childhood acute myeloid leukaemia [PDF]

open access: yes, 2017
Acute Myeloid Leukaemia (AML) develops when there is a block in differentiation and uncontrolled proliferation of myeloid precursors, resulting in bone marrow failure.
Gibson, Brenda E.S.   +3 more
core   +1 more source

Maladaptive plasticity in levodopa-induced dyskinesias and tardive dyskinesias: old and new insights on the effects of dopamine receptor pharmacology. [PDF]

open access: yes, 2014
Maladaptive plasticity can be defined as behavioral loss or even development of disease symptoms resulting from aberrant plasticity changes in the human brain.
Ahmed   +58 more
core   +2 more sources

Negative effects of abuse of laxatives in medical practice

open access: yesGastroenterologìa, 2018
The abuse of laxatives is a disorder characterized by an incomprehensible and changing range of gastrointestinal, electrolytic and acid-base abnormalities that can lead to both the onset of chronic diseases and fatalities.
Yu.M. Stepanov   +2 more
doaj   +1 more source

Modeling Autistic Features in Animals [PDF]

open access: yes, 2011
A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core   +1 more source

Menstrual cycle abnormalities in patients with prolactinoma and drug-induced hyperprolactinemia

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Background and Objective: Hyperprolactinemia affects the reproductive endocrine axis; however, the degree of dysfunction may vary depending on etiology.
Bindu Kulshreshtha   +6 more
doaj   +1 more source

Study of Cytogenetic Effects of Cimetidine Drug in White mice (Mus musculus) [PDF]

open access: yesEngineering and Technology Journal, 2017
This study aimed to detect the cytogenetic effects of Cimetidine drug, which used in the treatment of gastric ulceration, reflux oesophagitis through the tests (mitotic index of Somatic cells in bone marrow and spleen, frequency of micronuclei ...
T.G. Mohamed, A.A. Mohamed
doaj   +1 more source

Pancreatitis following Olanzapine Therapy: A Report of Three Cases [PDF]

open access: yes, 2007
CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being ...
Azar, Riad   +3 more
core   +4 more sources

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L.   +7 more
core   +3 more sources

Erupción fija por luz solar, una serie de 13 casos en Bogotá, Colombia

open access: yesActas Dermo-Sifiliográficas
Resumen: Desde 1975 se han publicado algunos casos que asocian la radiación ultravioleta como un desencadenante de erupciones cutáneas fijas (erupción o exantema fijo por luz solar o síndrome de fotosensibilidad localizada de amplio espectro ...
M.C. Valbuena   +2 more
doaj   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

open access: yes, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David   +8 more
core   +3 more sources

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