Results 61 to 70 of about 5,793,514 (248)
Drug Exposure During Pregnancy: A Case-Control Study from a Primary Care Database
Objective: Drug exposure during pregnancy is frequent, even more during first trimester as pregnant women might not be aware of their condition. We used available electronic health records (EHRs) to describe the use of medications during the first ...
Ainhoa Gomez-Lumbreras +6 more
doaj +3 more sources
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Drug-Induced Liver Injury in HIV Patients
The treatment of HIV has improved over the last decade due in part to the success of treatment with combination-therapy drug "cocktails," better referred to as highly active antiretroviral therapy.
Jayaweera, Dushyantha +2 more
core +4 more sources
Efeitos da amiodarona na tiróide. Aspectos actuais.
Amiodarone is a benzofuranic-derivate iodine-rich drug widely used for the treatment of tachyarrhythmias. In 14-18% of amiodarone-treated patients, there is overt thyroid disfunction, either amiodarone-induced hyperthyroidism (AIT) or amiodarone-induced ...
Maria Vítor Campos
doaj +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Announcement -- Agenda -- Breakout Sessions: Questions and Responses -- An Ounce of Understanding is Worth a Pound of Cure / by Kyle E. Murray -- Induced Seismicity and the Oil and Gas Industry -- Overview of Kansas Earthquakes / Rick Miller, Shelby ...
Induced Seismicity State Task Force Meeting (2014 : Wichita, Kan.)
core +1 more source
A systematic review of ECG findings in patients with COVID-19
Introduction: Since the epidemic of COVID-19 attracted the attention, reports were surrounding electrocardiographic changes in the infected individuals.
Esmaeil Mehraeen +7 more
doaj +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Background: Cellular repolarization abnormalities occur unpredictably due to disease and drug effects, and can occur even in cardiomyocytes that exhibit normal action potentials (AP) under control conditions.
Oliver J. Britton +4 more
doaj +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source

