Results 251 to 260 of about 356,562 (324)

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Management of drug-induced liver injury associated with anti-cancer therapy. [PDF]

Front Physiol
Vincenzi B, Yimin M, Andrade RJ, Morales Castillo M, Akhundova-Unadkat G, Mato JM.   +5 more
europepmc   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

GPR35 prevents drug-induced liver injury via the Gαs-cAMP-PKA axis in macrophages. [PDF]

Cell Mol Life Sci
Zhao X, Li Y, Yang L, Chen X, Zhang J, Chen T, Wang H, Li F, Cheng C, Wu J, Cong J, Yin W, Li J, Wang X.   +13 more
europepmc   +1 more source

Drug and herb induced liver injury: Council for International Organizations of Medical Sciences scale for causality assessment

, 2014
Rolf Teschke, Albrecht Wolff, Christian Frenzel, Alexander Schwarzenboeck, Johannes Schulze, Axel Eickhoff   +5 more
openalex   +1 more source

Biomimetic 3D‐Printed Adaptive Hydrogel Bioadhesives Featuring Superior Infection Resistance for Challenging Tissue Adhesion, Hemostasis, and Healthcare

Advanced Materials, EarlyView.
Biomimetic 3D‐printed hydrogel bioadhesives (PTLAs) are designed to address the limitations of existing bioadhesives, offering solutions for challenging tissue adhesion and enhanced healthcare. These PTLAs feature robust wet/underwater tissue adhesion/sealing, superior freeze/pressure and infection resistance, and adaptive self‐healing/gelling capacity,
Qi Wu, Meenakshi Chauhan, Bassma Khamaisi, Eid Nassar‐Marjiya, Shady Farah   +4 more
wiley   +1 more source

Drug-Induced Liver Injury: Mechanisms, Diagnosis, and Management: A Review.

J Pharm Bioallied Sci
Keshari AC, Thitame SN, Aher AA, Keshari UC.   +3 more
europepmc   +1 more source

The association between the gut microbiome and antituberculosis drug-induced liver injury. [PDF]

Front Pharmacol
Pei S, Yang L, Gao H, Liu Y, Lu J, Dai EH, Meng C, Feng F, Wang Y.   +8 more
europepmc   +1 more source

Volumetric 3D Printing and Melt‐Electrowriting to Fabricate Implantable Reinforced Cardiac Tissue Patches

Advanced Materials, EarlyView.
This study presents an implantable reinforced cardiac patch (RCPatch) combining volumetrically 3D‐printed metamaterials with melt‐electrowritten (MEW) meshes. The design integrates tunable stiff polymer structures with soft, cell‐laden hydrogels. The RCPatch withstands suturing, intraventricular pressure, and cardiac contraction in a large animal ...
Lewis S. Jones, Hector Rodriguez Cetina Biefer, Manuel Mekkattu, Quinten Thijssen, Alessio Amicone, Anna Bock, Miriam Weisskopf, Dennis Zorndt, Debora Meier, Li Zheng, Melanie Generali, Robert K. Katzschmann, Omer Dzemali   +12 more
wiley   +1 more source

Acute liver failure from anti-tuberculosis drug-induced liver injury: An update. [PDF]

World J Hepatol
Kumar R, Kumar A, Kumar S.
europepmc   +1 more source