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Veterinary Clinics of North America: Small Animal Practice
Drug-induced liver injury (DILI) is an underrecognized cause of hepatic disease in dogs and cats. Successful identification of cases requires an initial suspicion by the practitioner, a thorough drug exposure history, and knowledge of the toxic potential for common veterinary drugs.
Mariana Mesquita +2 more
+5 more sources
Drug-induced liver injury (DILI) is an underrecognized cause of hepatic disease in dogs and cats. Successful identification of cases requires an initial suspicion by the practitioner, a thorough drug exposure history, and knowledge of the toxic potential for common veterinary drugs.
Mariana Mesquita +2 more
+5 more sources
Drug-Induced Liver Injury - Types and Phenotypes.
New England Journal of Medicine, 2019Drug-Induced Liver Injury The liver has a range of responses to drug-induced injury, with a number of phenotypes.
J. Hoofnagle, E. Björnsson
semanticscholar +1 more source
Anticancer drugs are the first cause of drug‐induced liver injury in a reference hospital
Liver international (Print), 2023Drug‐induced liver injury (DILI) is a challenging liver disorder for hepatologists. We aimed to assess the pattern and causes of DILI in a tertiary hospital. We registered prospectively all patients referred with suspicion of DILI from 2018 to 2023.
A. Pocurull +13 more
semanticscholar +1 more source
Drug‐Induced Liver Injury After Liver Transplantation
Liver Transplantation, 2020Drug‐induced liver injury (DILI) is an adverse reaction to many drugs in common use that in a liver transplantation (LT) recipient may cause graft dysfunction and may even lead to graft loss and the need for retransplantation. However, several potential clinical scenarios, such as graft rejection and infection, can confound the diagnosis of suspected ...
Miguel, Jiménez-Pérez +3 more
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Recent Progress in Fluorescent Sensors for Drug-Induced Liver Injury Assessment.
ACS Sensors, 2021Drug-induced liver injury (DILI) is a persistent concern in drug discovery and clinical medicine. The current clinical methods to assay DILI by analyzing the enzymes in serum are still not optimal.
Jiao Chen +7 more
semanticscholar +1 more source
Drug Safety, 2007
Drug-induced liver injury is a frequent cause of hepatic dysfunction. Reliably establishing whether the liver disease was caused by a drug requires the exclusion of other plausible causes and the search for a clinical drug signature. The drug signature consists of the pattern of liver test abnormality, the duration of latency to symptomatic ...
Gebran, Abboud, Neil, Kaplowitz
openaire +2 more sources
Drug-induced liver injury is a frequent cause of hepatic dysfunction. Reliably establishing whether the liver disease was caused by a drug requires the exclusion of other plausible causes and the search for a clinical drug signature. The drug signature consists of the pattern of liver test abnormality, the duration of latency to symptomatic ...
Gebran, Abboud, Neil, Kaplowitz
openaire +2 more sources
Drug-Induced Hepatotoxicity or Drug-Induced Liver Injury
Clinics in Liver Disease, 2009Drug-induced hepatotoxicity is underreported and underestimated in the United States. It is an important cause of acute liver failure. Common classes of drugs causing drug-induced hepatotoxicity include antibiotics, lipid lowering agents, oral hypoglycemics, psychotropics, antiretrovirals, acetaminophen, and complementary and alternative medications ...
Aaron J, Pugh +4 more
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Drug-Induced Liver Injury [PDF]
, 2010 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)Drug-induced liver injury (DILI) is a well known adverse reaction of many drugs. Direct toxic liver damage is associated with paracetamol toxicity
Einar S. Björnsson
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Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006
Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure.
Herbert L. Bonkovsky +3 more
openaire +3 more sources
Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure.
Herbert L. Bonkovsky +3 more
openaire +3 more sources
Medicine, 2011
Abstract Drug-induced liver injury (DILI) accounts for 9.5% of all suspected adverse drug reactions (ADRs) and for a significant proportion of fatal ADRs. DILI may be a direct toxic effect or an immunological reaction to either the drug or an active metabolite. Drugs can cause a diverse array of liver injury, which may be acute or chronic.
Adam D. Farmer, Alison Brind
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Abstract Drug-induced liver injury (DILI) accounts for 9.5% of all suspected adverse drug reactions (ADRs) and for a significant proportion of fatal ADRs. DILI may be a direct toxic effect or an immunological reaction to either the drug or an active metabolite. Drugs can cause a diverse array of liver injury, which may be acute or chronic.
Adam D. Farmer, Alison Brind
openaire +1 more source