Results 161 to 170 of about 3,173 (215)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Drug related problems: definitions and classification

EJHP Practice, 2005
openaire   +2 more sources

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An ABC of Drug-Related Problems

Drug Safety, 2000
The problems relating to the use of medicines are manifold. They may differ in pharmacological, pathological, epidemiological and legal respects, and may have different consequences, for example, as regards scientific study, regulation or rational use.
Meyboom, R.H.B., Lindquist, M, Egberts, A.C.G.   +2 more
openaire   +3 more sources

Drug-related problems in the elderly

Orvosi Hetilap, 2012
The aging population in developed countries is a growing problem nowadays. The burden on healthcare is particularly high, since the prevalence of the diseases, especially chronic diseases increases with age. Prevalence of polypharmacy is common among elderly patients.
Andrea, Bor, Mária, Matuz, Péter, Doró, Réka, Viola, Gyöngyvér, Soós   +4 more
openaire   +2 more sources

Drug-related problems at the heart of cardiac surgery

European Journal of Hospital Pharmacy, 2023
Optimal perioperative success in cardiac surgery requires precise management of drug treatment. This study aimed to determine the prevalence, types and associated factors of drug-related problems (DRPs) during the entire hospital stay.A prospective observational study was conducted at the department of cardiovascular surgery in a university hospital ...
Burcu Kelleci Cakir, Ahmet Aydın, Mustafa Yılmaz, Aygin Bayraktar-Ekincioglu   +3 more
openaire   +2 more sources

Drug-Related Problems: Their Structure and Function

DICP, 1990
In order to better focus the role of the pharmacist on patient need and patient outcome, a means of categorizing drug-related problems (DRPs) is presented. A DRP exists when a patient experiences or is likely to experience either a disease or symptom having an actual or suspected relationship with drug therapy.
L M, Strand, P C, Morley, R J, Cipolle, R, Ramsey, G D, Lamsam   +4 more
openaire   +2 more sources

Drug-Related Problem Classification Systems

Annals of Pharmacotherapy, 2004
OBJECTIVE To provide an overview of and critically appraise classifications of drug-related problems (DRPs) for use during the pharmaceutical care process and research in pharmacy. DATA SOURCES A literature search was conducted using ...
van Mil, JW Foppe, Westerlund, LO Tommy, Hersberger, Kurt E, Schaefer, Marion A   +3 more
openaire   +3 more sources

Drug-Related Problems on a Palliative Care Unit

Journal of Pain & Palliative Care Pharmacotherapy, 2021
Pharmacotherapy is essential in palliative medicine. Besides potential benefits, pharmacotherapy also poses potential risks that need to be minimized for patient safety. Pharmacists can play an important role in identifying, solving, and avoiding drug-related problems (DRPs).
Constanze Rémi, Dominik Bauer*, Lisa Krumm, Claudia Bausewein   +3 more
openaire   +2 more sources

IATROGENESIS IN THE ELDERLY: Drug-Related Problems

Journal of Gerontological Nursing, 1991
Drug reactions are generally related to the influence of age, toxicity, side effects, immunologic reactions, idiosyncratic reactions, drug-drug interactions, and drug-disease interactions. In addition to age-related changes, the elderly are susceptible to the incidence of adverse drug reactions because of polypharmacy, incorrect self-administration of ...
J M, Stolley, K C, Buckwalter, B, Fjordbak, S, Bush   +3 more
openaire   +2 more sources