Results 181 to 190 of about 523,570 (260)

Effectiveness of a pharmacist-led tele-psychiatric clinic in managing drug-related problems. [PDF]

J Pharm Policy Pract
Al Shakhori M, Arain S, Abdulsalim S, Salim Karattuthodi M, Al Dhamen M, Almutairi S, Thorakkattil SA, Alahmdi D, Kunhikatta V, AlJishi AS.   +9 more
europepmc   +1 more source

Machine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems

Advanced Science, EarlyView.
This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang   +6 more
wiley   +1 more source

Development and validation of a risk prediction tool for drug-related problems in pre-operative elective surgical patients (mediPORT): A case-control study. [PDF]

PLoS One
Clemens S, Simon C, Lauth W, Rose O, Zimmermann G, Gerner P, Dückelmann C, Flamm M, Pachmayr J.   +8 more
europepmc   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Being the nurse's eyes and ears: a mixed methods study of assistant nurses' perceptions of their role regarding drug-related problems in nursing homes. [PDF]

BMC Nurs
Thelin S, Borgström Bolmsjö B, Caleres G, Mattsson A, Craftman ÅG, Midlöv P, Modig S.   +6 more
europepmc   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Detection of Elevated Risk for Drug-Related Problems in the Hospital—The AMTS2 Risk Score. [PDF]

Dtsch Arztebl Int
Jung-Poppe L, Pfistermeister B, Nicolaus HF, Roggenhofer A, Altenbuchner A, Andrikyan W, Ströbel A, Schnitzer C, Dormann H, Maas R.   +9 more
europepmc   +1 more source

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

Advanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok, Jesús Valdés‐Hernández, Varinia Bernales, Alán Aspuru‐Guzik, Alex Zhavoronkov   +4 more
wiley   +1 more source

Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, parallel-group trial. [PDF]

Front Med (Lausanne)
Bischof T, Schmidt-Ilsinger A, Hoppel M, Kreuzer A, Briganser S, Saiko P, Ergott-Badawi S, Podroschko R, Moser S, Kossmeier M, Jilma B, Deibl S, Schoergenhofer C.   +12 more
europepmc   +1 more source