Results 101 to 110 of about 2,925,110 (170)

Adverse drug reactions following treatment of latent tuberculosis infection: a linked national tuberculosis surveillance with claims database [PDF]

The Korean Journal of Internal Medicine
Background/Aims Few real-world studies explored factors associated with latent tuberculosis infection (LTBI) treatment-related adverse drug reactions (ADRs).
Yu-Seon Jung, Sun-Young Jung, Jae-Eun Lee, Kyungeun Lee, Jae Chol Choi   +4 more
doaj   +1 more source

HODDI: A Dataset of High-Order Drug-Drug Interactions for Computational Pharmacovigilance [PDF]

arXiv
Drug-side effect research is vital for understanding adverse reactions arising in complex multi-drug therapies. However, the scarcity of higher-order datasets that capture the combinatorial effects of multiple drugs severely limits progress in this field. Existing resources such as TWOSIDES primarily focus on pairwise interactions.
arxiv  

Supervised Adverse Drug Reaction Signalling Framework Imitating Bradford Hill's Causality Considerations [PDF]

Journal of Biomedical Informatics, 56 , pp. 356-368, 2015, 2016
Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when analysing longitudinal observational data. Due to these complexities, existing methods for large-scale detection of
arxiv  

Research on Adverse Drug Reaction Prediction Model Combining Knowledge Graph Embedding and Deep Learning [PDF]

arXiv
In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent prediction models need to be constructed for each adverse reaction of drugs, and the prediction accuracy is low, this ...
arxiv  

Introduction and reconciliation of the ROS and aging paradoxes [PDF]

arXiv, 2017
This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse circumstances. ROS may be more closely correlated with metabolism rather than aging.
arxiv  

Effectiveness and safety of protease inhibitors for the hepatitis C treatment in a hospital of South Brazil: real life data

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
Introduction: The combination of Inhibitors of protease boceprevir (BOC) or telaprevir (TLV) concomitantly with peginterferon (PEG) and ribavirin (RBV) constitute the triple therapy (TT) for Hepatitis C treatment. Objective: To describe the experience of
Aline Bianca Borba Mattana, Karin Hepp Schwambach, Alberi Adolfo Feltrin, Mareni Rocha Farias, Carine Raquel Blatt   +4 more
doaj  

Bayesian model selection in logistic regression for the detection of adverse drug reactions [PDF]

arXiv, 2015
Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods. In this context, disproportionality measures are used. However, by projecting the data onto contingency tables, these methods become sensitive to the problem ...
arxiv  

Adverse Drug Reactions Among Hospitalized Psychiatric Patients, Prevalence, Severity, Preventability, and Opportunities for Intervention

Oman Medical Journal
Objectives: The objective of this study was to boost pharmacovigilance activity in our psychiatry referral hospital and highlight the pharmacist's role in preventing, detecting, and managing adverse drug reactions (ADRs).
Asma Al Hindi, Sara Al Balushi, Sharifa Al Ruzaiqi, Shaima Al Busafi, Samah Abdulmonem, Iman M. Ali, Bushra Al Hindi, Diaa Al Rahmany   +7 more
doaj   +1 more source

A Large-Scale CNN Ensemble for Medication Safety Analysis

, 2017
Revealing Adverse Drug Reactions (ADR) is an essential part of post-marketing drug surveillance, and data from health-related forums and medical communities can be of a great significance for estimating such effects.
A Sarker, A Sarker, H Gurulingappa, WYS Chou   +3 more
core   +1 more source

Optimal Control For Anti-Abeta Treatment in Alzheimer's Disease using a Reaction-Diffusion Model [PDF]

arXiv
Alzheimer's disease is a progressive neurodegenerative disorder that significantly impairs patient survival and quality of life. While current pharmacological treatments aim to slow disease progression, they remain insufficient in halting cognitive decline.
arxiv