Results 111 to 120 of about 310,100 (285)

Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]

, 2009
This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Drug Hypersensitivity Associated with Dental Treatments

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To characterize drug hypersensitivity associated with dental treatments. Material and Methods: Data from 5,302 dental patients extracted from the Faculty of Dental Medicine were used to investigate drug use history, drug hypersensitivity, and ...
Ricardo Dias de Castro, Mariana Bezamat, Alexandre Rezende Vieira   +2 more
doaj  

Issues potentially affecting quality of life arising from long-term medicines use: a qualitative study [PDF]

, 2013
Background Polypharmacy is increasing and managing large number of medicines may create a burden for patients. Many patients have negative views of medicines and their use can adversely affect quality of life.
A Alic, A Bowling, A Thompson, B Guthrie, BA Golomb, C Anderson, C Fox, C Salisbury, CA Anderson, CE Eades, DC Berry, DT Eton, DT Eton, F Stevenson, J Krska, J Krska, J Krska, J Krska, J Krska, JW Saultz, K Cox, L Ong, M May, MA Boustani, MA Hassali, MG Duerden, MJ Atkinson, N Britten, N Mead, P Pound, PA Rochon, R Adler, R Horne, RA Elliott, RA Elliott, S Kripalani, S Williams, SE Campbell, SN Weingart, T Kairuz, V Nunes   +40 more
core   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Incidence of Potential Drug-Drug Interaction and Related Factors in Hospitalized Neurological Patients in two Iranian Teaching Hospitals

Iranian Journal of Medical Sciences, 2014
Background: Reciprocal drug interactions are among the most common causes of adverse drug reactions. We investigated the incidence and related risk factors associated with mutual drug interactions in relation to prescriptions written in the neurology ...
Soha Namazi, Shiva Pourhatami, Afshin Borhani-Haghighi, Sareh Roosta   +3 more
doaj  

A Large-Scale CNN Ensemble for Medication Safety Analysis

, 2017
Revealing Adverse Drug Reactions (ADR) is an essential part of post-marketing drug surveillance, and data from health-related forums and medical communities can be of a great significance for estimating such effects.
A Sarker, A Sarker, H Gurulingappa, WYS Chou   +3 more
core   +1 more source

A Drug Dosage Table is a Useful Tool to Facilitate Prescriptions of Antiretroviral Drugs for Children in Thailand. [PDF]

, 2005
Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors.
Eksaengsri, A, Frederix, K, Petdachai, W, Ponnet, M, Wilson, D, Zachariah, R   +5 more
core   +2 more sources

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

Advanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide, Claudia del Toro Runzer, Elena Della Bella, Christian Plank, Martijn van Griensven, Elizabeth Rosado Balmayor, Martin J. Stoddart, Matteo D'Este   +7 more
wiley   +1 more source

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah, Yu Qin, Mark A. Green, James D. E. T. Wilton‐Ely   +3 more
wiley   +1 more source