The Significance of the Ocular Adverse Effect Induced by Systemic Taxane Application
In recent years, in-depth research on anti-tumor therapy has brought the emergence of new active chemotherapeutic agents and combination regimens. However, as one of them, taxane drugs are widely used in clinical practice, but it should be noted that ...
Ya-Ting Ye +5 more
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Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]
This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
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Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
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Introduction: Chemotherapy-induced nausea and vomiting (CINV) are common adverse drug reactions (ADR) experienced by children undergoing treatment for cancer.
Elisangela Costa Lima +8 more
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Issues potentially affecting quality of life arising from long-term medicines use: a qualitative study [PDF]
Background Polypharmacy is increasing and managing large number of medicines may create a burden for patients. Many patients have negative views of medicines and their use can adversely affect quality of life.
A Alic +40 more
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Mood, Personality, and Behavior Changes During Treatment with Statins: A Case Series. [PDF]
Psychiatric adverse drug reactions (ADRs) have been reported with statin use, but the literature regarding statin-associated mood/behavioral changes remains limited.
Cham, Stephanie +2 more
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Mortality and years of life lost related to adverse drug events in Brazil [PDF]
OBJECTIVE To assess regional and national mortality and years of life lost (YLL) related to adverse drug events in Brazil. METHODS This is an ecological study in which death records from 2009 to 2018 from the Mortality Information System were analyzed.
Lunara Teles Silva +4 more
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A Drug Dosage Table is a Useful Tool to Facilitate Prescriptions of Antiretroviral Drugs for Children in Thailand. [PDF]
Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors.
Eksaengsri, A +5 more
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Case report: leg ulcers resolving after discontinuation of clozapine for schizophrenia.
There is a high prevalence of skin conditions and metabolic disturbances in patients with schizophrenia. Skin ulcers, in particular those of the lower extremities, mostly arise from arterial and/or venous pathology.
C Fragoeiro, C Machado, P Moura Ferreira
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