Results 41 to 50 of about 143,950 (267)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Adverse side-effects to biological agents

, 2006
Biological agents-like cytokines, monoclonal antibodies and fusion proteins are widely used in anti-inflammatory and tumour therapy. They are highly efficient in certain diseases, but can cause a great variety of adverse side-effects.
Pichler, W J
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Are we PREPAREd? Concerning the “PREemptive Pharmacogenomics Testing for Preventing Adverse Drug Reactions (PREPARE) Study”

Acta Médica Portuguesa, 2023
N/a.
Ana de Carmo Campos, Maria Luís Cardoso, Astrid Vicente   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Patients’ Needs and Expectations for the Application of Prevention of Drug-related Problems Prevention Programs

Journal of Research in Pharmacy Practice
Objective: Drug-related problems (DRPs) constitute a relevant health issue with a significant and escalating impact. The objective of this study is to identify the needs and expectations of patients benefiting from secondary prevention programs for DRPs ...
Ainhoa Vilarrubias Llopis, Jesús Ruiz-Ramos, Adrián Plaza Díaz, Mireia Puig Campmany, Anna Buisan Álvarez, Caterina Sampol-Mayol, Ana Juanes-Borrego   +6 more
doaj   +1 more source

Prevalência e características dos eventos adversos a medicamentos no Brasil

Cadernos de Saúde Pública, 2018
Resumo: O presente trabalho tem como objetivo descrever a prevalência e fatores associados a eventos adversos a medicamentos (EAM) referidos por usuários de medicamentos no Brasil.
Livia Alves Oliveira de Sousa, Marta Maria de França Fonteles, Mirian Parente Monteiro, Sotero Serrate Mengue, Andréa Dâmaso Bertoldi, Tatiane da Silva Dal Pizzol, Noemia Urruth Leão Tavares, Maria Auxiliadora Oliveira, Vera Lucia Luiza, Luiz Roberto Ramos, Mareni Rocha Farias, Paulo Sergio Dourado Arrais   +11 more
doaj   +1 more source

Case report: leg ulcers resolving after discontinuation of clozapine for schizophrenia.

Psicosomática y Psiquiatría, 2021
There is a high prevalence of skin conditions and metabolic disturbances in patients with schizophrenia. Skin ulcers, in particular those of the lower extremities, mostly arise from arterial and/or venous pathology.
C Fragoeiro, C Machado, P Moura Ferreira
doaj   +1 more source

“Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania [PDF]

, 2011
Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one
Shimwela, Grace Mng’ong’o
core