Results 31 to 40 of about 143,950 (267)

Levofloxacin-induced visual hallucinations: A case report and review of the literature [PDF]

open access: yesJournal of Health and Social Sciences, 2018
A 52-year-old female, nonalcoholic, with no significant past medical history, was empirically treated with intravenous administration of levofloxacin (LVFX, 750 mg/day) for bronchopneumonia.
Valentina Raffaelli   +3 more
doaj   +1 more source

Mortality and years of life lost related to adverse drug events in Brazil [PDF]

open access: yesRevista de Saúde Pública
OBJECTIVE To assess regional and national mortality and years of life lost (YLL) related to adverse drug events in Brazil. METHODS This is an ecological study in which death records from 2009 to 2018 from the Mortality Information System were analyzed.
Lunara Teles Silva   +4 more
doaj   +1 more source

Risk factors associated with adverse reactions to antituberculosis drugs [PDF]

open access: yesJornal Brasileiro de Pneumologia, 2015
This review sought to identify the available scientific evidence on risk factors associated with adverse reactions to antituberculosis drugs. We performed a systematic review of studies published in the 1965-2012 period and indexed in the MEDLINE and ...
Laíse Soares Oliveira Resende   +1 more
doaj   +4 more sources

Evaluating and Optimising the Retrieval of Research Evidence for Systematic Reviews of Adverse Drug Effects and Adverse Drug Reactions [PDF]

open access: yes, 2013
Systematic reviews can provide timely, reliable evidence on which to make informed decisions. In order to make balanced decisions, information is not only needed on the benefits of an intervention, but also on its adverse effects.
Golder, Su
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Side effects of chronic systemic glucocorticoid therapy: what dermatologists should know [PDF]

open access: yesAnais Brasileiros de Dermatologia
In dermatologists' clinical practice, the use of systemic glucocorticoids is recurrent for the management of different comorbidities that require chronic immunosuppression. The prescription of this medication requires caution and basic clinical knowledge
Lucas Campos Prudente Tavares   +2 more
doaj   +1 more source

The Utility of the Liverpool Adverse Drug Reaction Assessment Tools in the Evaluation of Chemotherapy-Induced Nausea and Vomiting in Children

open access: yesRevista Brasileira de Cancerologia, 2023
Introduction: Chemotherapy-induced nausea and vomiting (CINV) are common adverse drug reactions (ADR) experienced by children undergoing treatment for cancer.
Elisangela Costa Lima   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Preventable adverse drug events in critically ill HIV patients: Is the detection of potential drug-drug interactions a useful tool?

open access: yesClinics, 2018
OBJECTIVES: The aim of this study was to develop a strategy to identify adverse drug events associated with drug-drug interactions by analyzing the prescriptions of critically ill patients.
Grazielle Viana Ramos   +3 more
doaj   +1 more source

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