Drug-target interaction - Open Access .click

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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino +2 more
exaly

Sparse Modeling to Analyze Drug–Target Interaction Networks

2018
Most drugs produce their phenotypic effects by interacting with target proteins, and understanding the molecular features that underpin drug-target interactions is crucial when designing a novel drug. In this chapter, we introduce the protocols that have driven recent advances in sparse modeling methods for analyzing drug-target interaction networks ...
openaire +2 more sources

Chemogenomic Approaches to Infer Drug–Target Interaction Networks

2012
The identification of drug-target interactions from heterogeneous biological data is critical in the drug development. In this chapter, we review recently developed in silico chemogenomic approaches to infer unknown drug-target interactions from chemical information of drugs and genomic information of target proteins.
openaire +2 more sources

CoaDTI: multi-modal co-attention based framework for drug-target interaction annotation