Results 101 to 110 of about 11,649,511 (362)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Injections of drugs into the lateral ventricle of the cat [PDF]
, 1954 W. Feldberg, S.L. Sherwood
openalex +1 more source
US Food and Drug Administration
The Palgrave Encyclopedia of Interest Groups, Lobbying and Public Affairs, 2021 Barbara Desanto
semanticscholar +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Teaching of Critical Analysis of Drug Advertisements to Medical Students [PDF]
, 2011 Background: Medical practitioners utilize drug promotional materials from pharmaceutical companies as a major source of information especially in developing countries.
Adiga, S, Bairy, KL, Chogtu, B, Nayak, V
core +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Characteristics of drug users who do or do not have care of their children
, 2004 Aims - To compare the relative frequency of eight indicators of problem drug use and potentially adverse social circumstances in drug using parents and non-parents and to explore whether a profile based on these characteristics differs according to ...
Advisory Council on the Misuse of Drugs +18 more
core +1 more source
Outcome-based pricing for new pharmaceuticals via rebates [PDF]
, 2020 The price of new brand-name prescription drugs has been rising fast in the United States. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year.
Adida, E
core