Results 121 to 130 of about 7,787,075 (304)

Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review

open access: yesJournal of Research in Medical Sciences, 2015
Sepsis is a systemic inflammatory response to infection. Sepsis, which can lead to severe sepsis, septic shock, and multiple organ dysfunction syndrome, is an important cause of mortality. Pathogenesis is extremely complex.
Guilang Zheng   +5 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Evaluation of the knowldege and practice of the third year student nurses about drugs by OSCE method

open access: yesنشریه پرستاری ایران, 2008
Background and Aim: One of the most important functions of nurses, which require preparation and powerful scientific background, skill in decision making and careful attention to drug laws is administration of the drugs to the patients.
Roya Dokoohaki   +4 more
doaj  

Simulation of mass transport during intraperitoneal chemotherapy : a parametrical model of single tumor nodules [PDF]

open access: yes, 2016
OBJECTIVES Patients with peritoneal carcinomatosis suffer from a widespread metastatic growth of tumor nodules in the peritoneal cavity. Although Intraperitoneal (IP) chemotherapy allows for higher intratumor concentrations of the cytotoxic agent ...
Ceelen, Wim   +4 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

What's Good for Washington: Fair Prescription Drug Pricing and the Biotechnology Industry [PDF]

open access: yes, 2003
The rising cost of prescription drugs is consuming an ever-larger portion of limited funds for basic health care and other important services in Washington state.
Rebecca Kavoussi
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Editorial

open access: yesDrug Analytical Research, 2023
Drug Analytical Research
doaj   +2 more sources

Jubilant Milan Šútovec [PDF]

open access: yesSlovenska Literatura, 2000
Štefan Drug
doaj  

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