Results 121 to 130 of about 5,671,792 (258)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Drug-related and drug misuse deaths in Northern Ireland, 2023.
Due to an error in the classification of Pregabalin and Gabapentin in previous reports (not counted in drug misuse deaths) a correction has been made to the number of drug misuse deaths from 2020 to 2022 previously ...
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ON THE RELATIONSHIP OF PRE-WAR WORKERS' NEWSPAPERS ON SLOVAK LITERATURE [PDF]
Štefan Drug
doaj
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Arizona Drug Threat Assessment
This report is a strategic assessment that addresses the status and outlook of the drug threat to Arizona. Analytical judgment determined the threat posed by each drug type or category, taking into account the most current quantitative and qualitative ...
United States National Drug Intelligence Center
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Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Illicit drug reporting system (IDRS): national report 2016
Summary The Illicit Drug Reporting System (IDRS) is a national illicit drug monitoring system intended to identify emerging trends of local and national concern in illicit drug markets.
National Drug and Alcohol Research Centre
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