Results 121 to 130 of about 7,787,075 (304)
Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review
Sepsis is a systemic inflammatory response to infection. Sepsis, which can lead to severe sepsis, septic shock, and multiple organ dysfunction syndrome, is an important cause of mortality. Pathogenesis is extremely complex.
Guilang Zheng +5 more
doaj
New drugs, old drugs - dear drugs, cheap drugs
Hirschel, Bernard, Garbino, Jorge
openaire +4 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Evaluation of the knowldege and practice of the third year student nurses about drugs by OSCE method
Background and Aim: One of the most important functions of nurses, which require preparation and powerful scientific background, skill in decision making and careful attention to drug laws is administration of the drugs to the patients.
Roya Dokoohaki +4 more
doaj
Simulation of mass transport during intraperitoneal chemotherapy : a parametrical model of single tumor nodules [PDF]
OBJECTIVES Patients with peritoneal carcinomatosis suffer from a widespread metastatic growth of tumor nodules in the peritoneal cavity. Although Intraperitoneal (IP) chemotherapy allows for higher intratumor concentrations of the cytotoxic agent ...
Ceelen, Wim +4 more
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
What's Good for Washington: Fair Prescription Drug Pricing and the Biotechnology Industry [PDF]
The rising cost of prescription drugs is consuming an ever-larger portion of limited funds for basic health care and other important services in Washington state.
Rebecca Kavoussi
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

