Results 111 to 120 of about 8,662,910 (358)
Southwest Border Violence: Issues in Identifying and Measuring Spillover Violence [PDF]
, 2010 [Excerpt] There has been a recent increase in the level of drug trafficking-related violence within and between the drug trafficking organizations in Mexico. This violence has generated concern among U.S.
Eddy, Mark +6 more
core +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Drug Cases Filed across the Alaska Court System, FY 2008–2017 [PDF]
, 2018 Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug-related court filings throughout the state of Alaska for the fiscal years (FY) 2008 through 2017 and the 10-year trend of misdemeanor and ...
Reinhard, Daniel
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Efficient solid-phase synthesis of 1,2,3-benzotriazin-4-ones with SynPhaseTM Lanterns
Journal of the Brazilian Chemical Society, 2003 We have developed a solid-phase synthesis of 1,2,3-benzotriazin-4-ones through cyclization of 2-aminobenzamides via diazotization. The development of an efficient synthesis is important from the viewpoint of drug discovery, considering the various ...
Makino Shingo +2 more
doaj
Drug screening at single-organoid resolution via bioprinting and interferometry [PDF]
, 2023 Peyton Tebon +14 more
openalex +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Automated drug identification system [PDF]
, 1974 System speeds up analysis of blood and urine and is capable of identifying 100 commonly abused drugs. System includes computer that controls entire analytical process by ordering various steps in specific sequences. Computer processes data output and has
Campen, C. F., Jr.
core +1 more source
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery [PDF]
, 2015 Yuxi Wang +9 more
openalex +1 more source