Results 151 to 160 of about 6,956,165 (310)

Arrests for Drug Offenses in Alaska: 2000–2011 [PDF]

open access: yes, 2014
REVISION NOTE: Following the publication of the fact sheet — “Arrests for Drug Offenses in Alaska: 2000-2012” — the Alaska Justice Statistical Analysis Center (AJSAC) was informed by the Alaska Department of Public Safety (DPS) that the UCR drug arrest ...
Parker, Khristy
core  

Editorial

open access: yesDrug Analytical Research, 2023
Drug Analytical Research
doaj   +2 more sources

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Waste of Mechanical Ventilators as a Biological Sample for Follow up of Biomarkers and Drugs [PDF]

open access: yesPharmaceutical Sciences, 2020
Maryam Khoubnasabjafari   +3 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

食品攙偽假冒之類型化──美國法的啟示 Typification of Food Adulteration -A Perspective on the Federal Food, Drug, and Cosmetic Act of the United States of America

open access: yes交大法學評論, 2020
邇來攙偽相關之食品安全事件頻傳,與攙偽、假冒刑罰構成要件有關之條文,亦即食品安全衛生管理法第15 條第一項第七款和同法第49 條之適用與討論也逐漸增加,然由於食品安全衛生管理法第15 條第一項第七款條文用 字過於精簡,導致實務與學說有諸多相異之觀點,至今無法統一。美國聯邦食品、藥品與化妝品法對於攙偽之規範採取比較詳盡的定義模式,共列有數十種攙偽之行為樣態,值得我國借鑑,本文將以比較法研究之方式,分析其內涵、適用狀況與相關批評,再與我國現行食品安全衛生管理法第15 條第一項各款進行對照 ...
黃于容 Yu-Jung Huang   +1 more
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Extracting adverse drug reactions and their context using sequence labelling ensembles in TAC2017

open access: yes, 2018
Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration.
Belousov, Maksim   +3 more
core  

Jubilant Milan Šútovec [PDF]

open access: yesSlovenska Literatura, 2000
Štefan Drug
doaj  

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