Results 151 to 160 of about 8,662,910 (358)

Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier

, 2016
David S. Hersh, Aniket S. Wadajkar, Nathan B. Roberts, Jimena G. Perez, Nina P. Connolly, Victor Frenkel, Jeffrey A. Winkles, Graeme F. Woodworth, Anthony J. Kim   +8 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

For the literary historian and critic Ivan Kusý [PDF]

Slovenska Literatura, 2000
Štefan Drug
doaj  

Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors

, 2019
Sajini D. Hettiarachchi, Regina M. Graham, Keenan J. Mintz, Yiqun Zhou, Steven Vanni, Zhilli Peng, Roger M. Leblanc   +6 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The symbiosis of poetry and politics after the World War II. – 2nd part [PDF]

Slovenska Literatura, 2001
Štefan Drug
doaj  

Ferritin nanocages: A biological platform for drug delivery, imaging and theranostics in cancer

, 2016
Marta Truffi, Luisa Fiandra, Luca Sorrentino, Matteo Monieri, Fabio Corsi, Serena Mazzucchelli   +5 more
openalex   +2 more sources

Development of Chitosan Nanoparticles as a Stable Drug Delivery System for Protein/siRNA [PDF]

, 2013
Haliza Katas, Maria Abdul Ghafoor Raja, Kai Leong Lam   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A reliable literary historian, colleague and friend [PDF]

Slovenska Literatura, 2001
Štefan Drug
doaj