Results 211 to 220 of about 8,662,910 (358)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden. [PDF]

Basic Clin Pharmacol Toxicol
Asker F, Gimerus S, Parodi López N, Wallerstedt SM.   +3 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development: A Clinician’s Request for a More Integrated Approach [PDF]

, 2012
Karel Allegaert, Anne Smits, Johannes N. van den Anker   +2 more
openalex   +1 more source

Aging, Drugs, and Drug Metabolism [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2011
David G, Le Couteur, Andrew J, McLachlan, Rafael, de Cabo   +2 more
openaire   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Bullous fixed drug eruption associated with ibuprofen. [PDF]

CMAJ
Wen HY, Gao XH.
europepmc   +1 more source

Fabrication of a hyaluronic acid conjugated metal organic framework for targeted drug delivery and magnetic resonance imaging

, 2018
Fangpeng Shu, Daojun Lv, Xian‐Lu Song, Bin Huang, Chong Wang, Yu‐Zhong Yu, Shan‐Chao Zhao   +6 more
openalex   +2 more sources

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

A Review of Exercise Interventions for Rehabilitation in Drug-Dependent Individuals. [PDF]

Addict Biol
He Q, Zhu L, Wang Z, Wang H, Jiang Y, Wang X, Luo F, Zhu C, Zhan C.   +8 more
europepmc   +1 more source

RETRACTED: Magnetic Properties of Polyvinyl Alcohol and Doxorubicine Loaded Iron Oxide Nanoparticles for Anticancer Drug Delivery Applications

, 2016
Muhammad Nadeem, Munir Ahmad, Muhammad Saeed Akhtar, A. Shaari, Saira Riaz, Shahzad Naseem, Misbah Masood, M. A. Saeed   +7 more
openalex   +2 more sources