Drug-therapy networks and the predictions of novel drug targets [PDF]
Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the effects of drugs on the robustness of cellular networks.
arxiv +1 more source
Arrests for Drug Offenses in Alaska: 2000-2011 [PDF]
This fact sheet presents data on arrests for drug offenses made by Alaska police agencies for the period 2000 through 2011. The report presents drug offense arrest information for both adults and juveniles for the 12-year period, including number of drug
Myrstol, Brad A.
core
Parents, Peers, and Campus Involvement in the Transition to College
The purpose of this research was to examine factors that contribute to a successful transition into college. It acknowledges the importance of parents, peers, and campus involvement during this developmental period. Ninety-six college freshmen were given
Jacquelyn M. Norris, Nina S. Mounts
doaj +1 more source
Graph Distance Neural Networks for Predicting Multiple Drug Interactions [PDF]
Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent drug-drug interactions.
arxiv
Drug Sale and Manufacture Arrests Reported in Alaska, 1986–2017 — Drug Types by Sex [PDF]
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale and manufacture arrests by type of drug and sex of arrestee as reported by Alaska law enforcement agencies for the 32-year period 1986 ...
Ervin, Benjamin
core
Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L.+4 more
core +3 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Market Analysis of Plant-based Drugs C. The Cannabis Market [PDF]
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...
core
FUNCTIONAL ANALYSIS OF THE WEBBING USED IN AUTO SEATBELTS [PDF]
The reason this paper was made was to identify the functions with the highest importance factor of webbing used in auto seatbelts. For these functions to satisfy all the requirements of operating, functions resulted from analyzing the properties of the ...
DRUG (LUCA) Alexandra, CIOARĂ Ioan
doaj
Behavioral Changes Over Time Following Ayahuasca Exposure in Zebrafish
The combined infusion of Banisteriopsis caapi stem and Psychotria viridis leaves, known as ayahuasca, has been used for centuries by indigenous tribes.
Robson Savoldi+7 more
doaj +1 more source