Results 1 to 10 of about 435,266 (312)

Impact of COVID-19 on drug markets, use, harms and drug services in Europe

open access: yesJournal of Geography, Politics and Society, 2022
Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets
Alessandro Pirona   +12 more
doaj   +1 more source

Benzodiazepine Use in Opioid Maintenance Treatment Programme: Risks and Clinical Outcomes

open access: yesActa Médica Portuguesa, 2021
Introduction: The co-association of benzodiazepines and opioids is associated with an increased risk of overdose, death, and poorer psychosocial prognosis.
Catarina Oliveira   +7 more
doaj   +1 more source

Effects and associated transcriptomic landscape changes of methamphetamine on immune cells

open access: yesBMC Medical Genomics, 2022
Background Methamphetamine (METH) abuse causes serious health problems, including injury to the immune system, leading to increased incidence of infections and even making withdrawal more difficult.
Deshenyue Kong   +9 more
doaj   +1 more source

Current Concepts on Drug Abuse and Dependence [PDF]

open access: yes, 2015
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza   +5 more
core   +6 more sources

Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression

open access: yesScientific Reports, 2021
Psychiatric disorders such as anxiety and depression precipitated by substance use occurred during both use and withdrawal. Exosomes play significant roles in biological functions and regulate numerous physiological and pathological processes in various ...
Fengrong Chen   +13 more
doaj   +1 more source

Methamphetamine and HIV-Tat Protein Synergistically Induce Oxidative Stress and Blood-Brain Barrier Damage via Transient Receptor Potential Melastatin 2 Channel

open access: yesFrontiers in Pharmacology, 2021
Synergistic impairment of the blood-brain barrier (BBB) induced by methamphetamine (METH) and HIV-Tat protein increases the risk of HIV-associated neurocognitive disorders (HAND) in HIV-positive METH abusers.
Jian Huang   +19 more
doaj   +1 more source

Dynamic immune and exosome transcriptomic responses in patients undergoing psychostimulant methamphetamine withdrawal

open access: yesFrontiers in Cellular Neuroscience, 2022
Methamphetamine (METH) addiction and withdrawal cause serious harm to both the immune system and nervous system. However, the pathogenesis remains largely unknown.
Hongjin Wu   +13 more
doaj   +1 more source

Home - About - Disclaimer - Privacy