Results 21 to 30 of about 1,886,307 (248)
Frontiers in Behavioral Neuroscience, 2019 Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix® or Chantix®), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to ...
Vernon Garcia-Rivas +13 more
doaj +1 more source
, 2009 Many drugs of abuse, including cannabinoids, opioids, alcohol and nicotine, can alter the levels of endocannabinoids in the brain. Recent studies show that release of endocannabinoids in the ventral tegmental area can modulate the reward-related effects of dopamine and might therefore be an important neurobiological mechanism underlying drug addiction.
Zuzana, Justinova +2 more
openaire +2 more sources
Recreational Use of Nitrous Oxide – a Growing Concern in Europe
Emerging Trends in Drugs, Addictions, and HealthIntroduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais +16 more
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Carryover effects to addiction-associated stimuli in a group of marijuana and cocaine users [PDF]
, 2010 Addiction has been characterized as an attentional bias towards drug-related cues. In two experiments we investigate the effects of non-words that have been associatively trained to addiction-related images in a group of marijuana and cocaine users ...
Money, Sharon, Sharma, Dinkar
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Harm reduction in the Heartland: public knowledge and beliefs about naloxone in Nebraska, USA
Harm Reduction Journal, 2022 Background Opioid-related overdose deaths have been increasing in the United States (U.S.) in the last twenty years, creating a public health challenge.
Allison Schlosser +2 more
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κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats
Neurobiology of Stress, 2021 Although opioids are potent analgesics, a consequence of chronic opioid use is hyperalgesia during withdrawal, which may contribute to opioid misuse. Dynorphin, the endogenous ligand of κ-opioid receptors (KORs), is upregulated in opioid-dependent rats ...
Renata C.N. Marchette +8 more
doaj +1 more source
Associations of treatment completion against drug addiction with motivational interviewing and related factors in Afghanistan [PDF]
, 2018 2018-08Despite the increase in the number of drug treatment centers, patients with drug addicts have been increasing without the improvement of treatment in Afghanistan.
Hamajima, Nobuyuki +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Zhongguo gonggong weishengObjectiveTo understand the prevalence and influencing factors of nicotine dependence among rural elderly of Han, Dai, Hani, and Bai ethnicity in Yunnan province, to provide a reference for developing strategies to alleviate nicotine dependence symptoms ...
Guohui LI +7 more
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