Results 1 to 10 of about 1,886,307 (248)

Impact of COVID-19 on drug markets, use, harms and drug services in Europe

open access: yesJournal of Geography, Politics and Society, 2022
Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets
Alessandro Pirona   +12 more
doaj   +1 more source

Benzodiazepine Use in Opioid Maintenance Treatment Programme: Risks and Clinical Outcomes

open access: yesActa Médica Portuguesa, 2021
Introduction: The co-association of benzodiazepines and opioids is associated with an increased risk of overdose, death, and poorer psychosocial prognosis.
Catarina Oliveira   +7 more
doaj   +1 more source

Effects and associated transcriptomic landscape changes of methamphetamine on immune cells

open access: yesBMC Medical Genomics, 2022
Background Methamphetamine (METH) abuse causes serious health problems, including injury to the immune system, leading to increased incidence of infections and even making withdrawal more difficult.
Deshenyue Kong   +9 more
doaj   +1 more source

Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression

open access: yesScientific Reports, 2021
Psychiatric disorders such as anxiety and depression precipitated by substance use occurred during both use and withdrawal. Exosomes play significant roles in biological functions and regulate numerous physiological and pathological processes in various ...
Fengrong Chen   +13 more
doaj   +1 more source

Drug Addiction

open access: yesNeurobiology of Disease, 2000
George Koob
doaj   +3 more sources

Methamphetamine and HIV-Tat Protein Synergistically Induce Oxidative Stress and Blood-Brain Barrier Damage via Transient Receptor Potential Melastatin 2 Channel

open access: yesFrontiers in Pharmacology, 2021
Synergistic impairment of the blood-brain barrier (BBB) induced by methamphetamine (METH) and HIV-Tat protein increases the risk of HIV-associated neurocognitive disorders (HAND) in HIV-positive METH abusers.
Jian Huang   +19 more
doaj   +1 more source

Dynamic immune and exosome transcriptomic responses in patients undergoing psychostimulant methamphetamine withdrawal

open access: yesFrontiers in Cellular Neuroscience, 2022
Methamphetamine (METH) addiction and withdrawal cause serious harm to both the immune system and nervous system. However, the pathogenesis remains largely unknown.
Hongjin Wu   +13 more
doaj   +1 more source

Gray-matter structure in long-term abstinent methamphetamine users

open access: yesBMC Psychiatry, 2020
Background Previous studies of brain structure in methamphetamine users have yielded inconsistent findings, possibly reflecting small sample size and inconsistencies in duration of methamphetamine abstinence as well as sampling and analyses methods. Here
Lili Nie   +7 more
doaj   +1 more source

Comparative Analysis of Potential Risk Factors for at-Risk Gambling, Problem Gambling and Gambling Disorder among Current Gamblers—Results of the Austrian Representative Survey 2015

open access: yesFrontiers in Psychology, 2017
Background: The risk of developing a problem gambling behavior is distributed unequally among the population. For example, individuals who report stressful life events, show impairments of mental health or belong to a socio-economically deprived group ...
Sven Buth   +9 more
doaj   +1 more source

Course and Correlates of Stigma in Patients on Opioid Agonist Treatment: A Prospective Study from an Outpatient Treatment Program in India

open access: yesIndian Journal of Psychological Medicine, 2022
Background: Individuals with opioid dependence experience stigma and discrimination. Stigma can potentially reduce treatment-seeking and negatively affect treatment outcomes.
Abhishek Ghosh   +6 more
doaj   +1 more source

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