Results 111 to 120 of about 4,201,815 (397)

Exploring the link among state of mind concerning childhood attachment, attachment in close relationships, parental bonding, and psychopathological symptoms in substance users [PDF]

, 2016
In the present study, we have explored the link among styles of attachment and psychopathology in drug users. We know that insecure attachment predisposes the individuals the development of drug-addiction and psychopathological symptoms.
Corsano, Paola, Magnani, Barbara, Musetti, Alessandro, SALVATORE, Sergio, Terrone, Grazia   +4 more
core   +3 more sources

Uncovering mechanism of hepatotoxicity diseases caused by tetrahydrocannabinol based on novel network toxicology and experimental verification

Scientific Reports
This study systematically investigated the molecular mechanisms underlying tetrahydrocannabinol (THC)-induced hepatotoxicity in humans through an integrated approach combining network toxicology, molecular docking, and experimental validation.
Tiantian Zou, Ruilin Zhang, Liping Hu, Genmeng Yang, Xuanyu Chen, Mengqing Wang, Tiantian Cheng, Shengjie Nie, Linlin Liu, Shijun Hong   +9 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Individual differences in the neuropsychopathology of addiction. [PDF]

, 2017
Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
core  

Recreational Use of Nitrous Oxide – a Growing Concern in Europe

Emerging Trends in Drugs, Addictions, and Health
Introduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais, L. Van Aerts, M. Evans-Brown, A. Gallegos, R. Christie, R. Jorge, T. Néfau, G. Planchuelo, R. Sedefov, C. Victorri-Vigneau, R. Povilanskiene, K. Grasaasen, D.F.t. Palmqvis, D. Mongan, K. Killeen, A.O. Duarte, A.S. Santos   +16 more
doaj  

The Therapeutic Utility of Employment in Treating Drug Addiction: Science to Application.

Translational Issues in Psychological Science, 2016
Research on a model Therapeutic Workplace has allowed for evaluation of the use of employment in the treatment of drug addiction. Under the Therapeutic Workplace intervention, adults with histories of drug addiction are hired and paid to work. To promote
K. Silverman, August F. Holtyn, Reed Morrison   +2 more
semanticscholar   +1 more source

Drug Addiction [PDF]

New England Journal of Medicine, 2003
Cami, J., Farre, M.
openaire   +3 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Death by Dealer: When Addicts Overdose, Should Dealers Be Charged with Murder? [PDF]

, 2015
The nation is currently in the throes of an epidemic of opiate addiction. More Americans now die from fatal opiate overdoses than from automobile accidents every year -- and the problem is especially pronounced in white suburban, exurban, and rural ...
Patrick Radden Keefe
core  

Social poverty indicators with school bullying victimization: evidence from the global school-based student health survey (GSHS)

BMC Public Health
Background School bullying is prevalent in children and adolescents. Bullying victims are seen higher risk of negative psychological outcomes. Previously published studies suggested that social indicators may pose significant influence on bullying ...
Lin Chen, Ying Chen, Hailiang Ran, Yusan Che, Die Fang, Qiongxian Li, Yuanyu Shi, Shuqing Liu, Yandie He, Guiqing Zheng, Yuanyuan Xiao   +10 more
doaj   +1 more source