Results 181 to 190 of about 435,266 (312)

Identification of the socio-cultural barriers of drug addiction treatment in Iran. [PDF]

Heliyon, 2023
Razaghi E, Farhoudian A, Pilevari A, Noroozi A, Hooshyari Z, Radfar R, Malekinejad M.   +6 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Potential roles for microglia in drug addiction: Adolescent neurodevelopment and beyond. [PDF]

J Neuroimmunol
Martinez MX, Mahler SV.
europepmc   +1 more source

The Effects of Drug Addiction and Detoxification on the Human Oral Microbiota. [PDF]

Microbiol Spectr, 2023
Zhang J, Liu W, Shi L, Liu X, Wang M, Li W, Yu D, Wang Y, Zhang J, Yun K, Yan J.   +10 more
europepmc   +1 more source

Crime and the Labour Market: Evidence from a Survey of Inmates [PDF]

In this paper data from a survey of 1,771 inmates conducted in 31 German prisons provide microeconometric evidence on the relationship between individual anticipated labour market opportunities and the perceived probability of future recidivism.
Entorf, Horst
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Features of drug addiction treatment programs in Atlantic Canada that help (or not) with access and retention: A qualitative study. [PDF]

PLoS One
Mathias H, Jackson LA, Buxton JA, Dubé A, Kiepek N, MacDonald JA, Martin F, Smith J.   +7 more
europepmc   +1 more source

Current Acupuncture Research on Opiate Drug Addiction [PDF]

, 2018
Jiulin Wang, Xiaozhen Fan, Marc Raedschelders, Guojian Huang, Fulin Wang   +4 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Craving self-reports as outcome measures in drug addiction trials: A systematic review of ClinicalTrials.gov. [PDF]

Addiction
Toulami M, Ghasemi K, Rafei P, Sangchooli A, Nafissi N, Khojasteh Zonoozi A, Mohaddes Ardabili H, Ebrahimi M, Rezapour T, Ekhtiari H.   +9 more
europepmc   +1 more source