Results 241 to 250 of about 435,266 (312)

The Role of Orexin Receptor Antagonists in Inhibiting Drug Addiction: A Review Article. [PDF]

Addict Health
Esmaili-Shahzade-Ali-Akbari P, Ghaderi A, Sadeghi A, Nejat F, Mehramiz A.   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Drug Addiction in Gay and Bisexual Men Living with HIV Engaged in Sexualized Drug Use: Recent Drug Use, Polydrug and Depressive Symptoms as Predictors. [PDF]

AIDS Behav
Ollero MJF, Ryan P, Dolengevich-Segal H, Cano-Smith J, Ramos-Ruperto L, Cabello A, Sanchez-Conde M, Cabello N, Sanz J, García-Fraile LJ, Perez-Latorre L, Bisbal O, De La Fuente S, Losa JE, González-Baeza A.   +14 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nitazenes represent a growing threat to public health in Europe

The Lancet Public Health
Isabelle Giraudon, Katri Abel-Ollo, Diāna Vanaga-Arāja, Peter Heudtlass, Paul Griffiths   +4 more
doaj   +1 more source

Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking

, 2014
Jacqueline M. Barker, Jane R. Taylor, Taco J. De Vries, Jamie Peters   +3 more
openalex   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Enhancing the drug addiction treatment service by introducing a new residential treatment model in the Philippines: A qualitative study. [PDF]

Subst Abuse Treat Prev Policy
Kanamori S, Shirasaka T, Iñigo MT, Villaroman A, Noguera-Caoile R, Mizusawa A, Peralta J, Harada T.   +7 more
europepmc   +1 more source

Menace of drug addiction in the North-eastern states of India

, 1996
B. S. Nagi
openalex   +1 more source