Results 141 to 150 of about 2,902,189 (362)

National Comprehensive Trachoma Treatment Campaign: Community Monitoring of Mass Drug Administration (MDA) Coverage and Practices

, 2022
Hassan Abdulwahab Al-Shamahy
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Use of failure mode and effects analysis in improving the safety of i.v. drug administration [PDF]

, 2005
Wayne Adachi, Amy E. Lodolce
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Suspected adverse drug reactions of rivaroxaban reported in the United States food and drug administration adverse event reporting system database: a pharmacovigilance study [PDF]

Jingying Wu, Jianru Wu, Biyu Tang, Xinru Wang, Fenfang Wei, Yi Zhang, Limin Li, Hongqiao Li, Bei Wang, Wenyu Wu, Xiang Hong   +10 more
openalex   +1 more source

Particle size analysis: AAPS workshop report, cosponsored by the Food and Drug Administration and the United States Pharmacopeia

, 2020
Diane J. Burgess, Eric Duffy, Frank M. Etzler, Anthony J. Hickey   +3 more
openalex   +1 more source

MP73-01 SEQUENTIAL ADMINISTRATION OF BACILLUS CALMETTE-GUERIN (BCG) AND ELECTROMOTIVE DRUG ADMINISTRATION (EMDA) OF MITOMYCIN C (MMC) FOR THE TREATMENT OF HIGH GRADE NON MUSCLE INVASIVE BLADDER CANCER AFTER BCG FAILURE [PDF]

, 2020
Tristan Juvet, Christopher Wallis, Lior Krimus, Cynthia Kuk, Annette Erlich, Andrea Mari, Girish S. Kulkarni, Neil Fleshner, Alexandre R. Zlotta   +8 more
openalex   +1 more source

Intravesical electromotive drug administration

, 2005
"Iontophoresis" is the common term used to define the active transport of ionic molecules across biologic tissues under the influence of an electric field. The term "electro-osmosis" defines the subsequent transport of the solvent. The term "electrophoresis" indicates the transport of a solution and a solute, by means of an electric current ...
GIANNANTONI, Antonella, Di Stasi, Savino M, PORENA, Massimo, Stephen, Robert L.   +3 more
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon [PDF]

, 2020
Sharon Mumah Nyagang, Samuel Nambile Cumber, Jerome Fru Cho, Elsie Indah Keka, Claude Ngwayu Nkfusai, Emerson Wepngong, Joyce Mahlako Tsoka-Gwegweni, Eric B. Fokam   +7 more
openalex   +1 more source