Results 81 to 90 of about 577,363 (331)

Adverse events in different administration routes of semaglutide: a pharmacovigilance study based on the FDA adverse event reporting system

Frontiers in Pharmacology
BackgroundWith the continuously increasing incidence of type 2 diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists, known for their dual benefits of effectively controlling blood glucose levels while also reducing weight and lowering ...
Kaibin Niu, Maoxia Fan, Wulin Gao, Chen Chen, Guohua Dai   +4 more
doaj   +1 more source

24 Route of Administration and Drug Class Are Correlated With Length of Stay in Primary Headache Emergency Department Visits [PDF]

, 2021
P. Wang, Ryan Honomichl, Belinda Udeh, Michelle Campbell, Felipe Delgado, McKinsey R. Muir, Michael Phelan   +6 more
openalex   +1 more source

Fast Neutron Detector Based on Hybrid 2D Perovskite Thin Films

Advanced Functional Materials, EarlyView.
This work presents the direct detection of fast neutrons using flexible hybrid 2D perovskite (PEA2PbBr4) thin‐film detectors. Thanks to their high low‐Z elements content and good charge transport, these materials enable efficient neutron detection. The thin film configuration allowed the operation at low voltage, and offer scalability, flexibility, and
Ilaria Fratelli, Felix Pino, Laura Basiricò, Giulia Napolitano, Jessica Carolina Delgado, Sara Cepić, Andrea Ciavatti, Sandra Moretto, Gianluigi Maggioni, Marco Cinausero, Sara Maria Carturan, Beatrice Fraboni   +11 more
wiley   +1 more source

Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. [PDF]

Int J Mol Sci, 2023
Fries F, Kany AM, Rasheed S, Hirsch AKH, Müller R, Herrmann J.   +5 more
europepmc   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Electrochemotherapy with intravenous, intratumoral, or combined administration of bleomycin in the treatment of colorectal hepatic metastases in a rat model

Scientific Reports
Electrochemotherapy (ECT) combines the reversible electroporation (rEP) with intravenous (i.v.) or intratumoral (i.t.) administration of chemotherapeutic drugs. We conducted this study to compare the efficacy of i.v., i.t., and i.v. + i.t.
Antonios E. Spiliotis, Sebastian Holländer, Gudrun Wagenpfeil, Robert Eisele, Spyridon Nika, Orestis Mallis Kyriakides, Matthias W. Laschke, Michael D. Menger, Matthias Glanemann, Gereon Gäbelein   +9 more
doaj   +1 more source

Study of the Pharmacokinetics and Safety of Dioxidine®, Solution for Topical and External Use, 0.25 mg/ml, in Various Routes of Administration

Антибиотики и Химиотерапия
Topical use of antibacterial drugs as part of complex therapy for purulent-inflammatory infections of the skin and oropharynx can not only eliminate the symptoms but also influence the cause of the disease.
V. A. Stepanov, S. V. Ponasenkova, E. S. Simonova, P. D. Sobolev, A. G. Nikiforova, A. A. Globenko, A. V. Kapashin, M. A. Pasko   +7 more
doaj   +1 more source

Nanotechnology Based Approaches for Enhancing Oral Bioavailability of Poorly Water Soluble Antihypertensive Drugs

Scientifica, 2016
Oral administration is the most convenient route among various routes of drug delivery as it offers high patient compliance. However, the poor aqueous solubility and poor enzymatic/metabolic stability of drugs are major limitations in successful oral ...
Mayank Sharma, Rajesh Sharma, Dinesh Kumar Jain   +2 more
doaj   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Nanofillers Reinforcing Biopolymer Composites for Sustainable Food Packaging Applications: A State‐of‐the‐Art Review

Advanced Functional Materials, EarlyView.
Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya, Joydeep Dutta, Santosh Kumar   +2 more
wiley   +1 more source