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Drug Allergy

Allergy and Asthma Proceedings, 1990
Undesirable or adverse drug effects occur with 1-15% of drug doses. The mechanisms of these reactions are not always known; however, 5-10% are immunologically mediated allergic reactions. Risk factors for allergic drug reactions include age, type of drug, degree of exposure, and route of administration.
K, Kim, R, Evans, T A, Mahr
openaire   +2 more sources

Drug allergy

Allergy and Asthma Proceedings, 2019
Drug allergy describes clinical adverse reactions that are proved or presumed to be immunologically based. Allergic drug reactions do not resemble pharmacologic actions of the incriminated drug and may occur at fractions of what would be the therapeutic dosage.
Chitra, Dinakar   +2 more
openaire   +4 more sources

Drug Allergy

Primary Care: Clinics in Office Practice, 2016
An adverse drug reaction relates to an undesired response to administration of a drug. Type A reactions are common and are predictable to administration, dose response, or interaction with other medications. Type B reactions are uncommon with occurrences that are not predictable.
Abdul, Waheed   +2 more
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Pediatric Drug Allergy

Immunology and Allergy Clinics of North America, 2022
Drug allergies are reported in approximately 10% of children and carry significant health and economic impacts. However, only a minority of these reported drug allergies are established on diagnostic workup. Classically, drug allergies were diagnosed by skin prick and/or intradermal tests.
Connor, Prosty   +4 more
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Drug allergy

Current Opinion in Allergy and Clinical Immunology, 2001
Drug allergies can cause a great variety of symptoms and can thus imitate various diseases, like in previous times the lues. Drug allergies can be classified into three subgroups, which differ in their pathophysiology and require different diagnostic steps: firstly, classical drug allergies which are directed to the drug itself, a reactive compound of ...
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Allergy to Drugs

New England Journal of Medicine, 1951
THE seventeenth century must have been the nadir of therapeutics, if we can believe Moliere, for one of his characters remarks: "Almost everyone dies of the remedy, not the malady." Fortunately, si...
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DRUG ALLERGIES

Primary Care: Clinics in Office Practice, 1998
Allergic drug reactions are a significant cause of morbidity and mortality. Because it is difficult to identify the culprit drug and the underlying pathophysiologic mechanisms involved in these reactions, a systematic approach should be adopted in the evaluation of drug-allergic patients. Initially, the type of reaction should be determined.
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Drug allergy

Journal of Allergy and Clinical Immunology, 2010
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to
David A, Khan, Roland, Solensky
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Drug allergy

Medical Clinics of North America, 1992
Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions.
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Eosinophilic Drug Allergy

Clinical Reviews in Allergy & Immunology, 2015
While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex ...
Merin, Kuruvilla, David A, Khan
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