Results 241 to 250 of about 2,169,014 (281)
Some of the next articles are maybe not open access.
Journal of Allergy and Clinical Immunology, 2010
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to
David A, Khan, Roland, Solensky
openaire +2 more sources
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to
David A, Khan, Roland, Solensky
openaire +2 more sources
Clinical Reviews in Allergy & Immunology, 2015
While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex ...
Merin, Kuruvilla, David A, Khan
openaire +2 more sources
While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex ...
Merin, Kuruvilla, David A, Khan
openaire +2 more sources
Medical Clinics of North America, 1992
Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions.
openaire +2 more sources
Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions.
openaire +2 more sources
Immunology Today, 1998
Abstract Against the background of advances in our knowledge of antigen recognition at the molecular level, a recent meeting1The International Symposium on Adverse Drug Reactions with an Immunological Basis was held at Puerto de Santa Maria, Spain, on 19–22 November 1997. 1 reconsidered how the immune system recognizes and responds to drugs.
J W, Coleman, M, Blanca
openaire +2 more sources
Abstract Against the background of advances in our knowledge of antigen recognition at the molecular level, a recent meeting1The International Symposium on Adverse Drug Reactions with an Immunological Basis was held at Puerto de Santa Maria, Spain, on 19–22 November 1997. 1 reconsidered how the immune system recognizes and responds to drugs.
J W, Coleman, M, Blanca
openaire +2 more sources
Immunology and Allergy Clinics of North America, 2014
Poorly documented and often self-reported drug hypersensitivity (DH) is a frequent problem in daily clinical practice and has a considerable impact on prescription choices. Little is known about the natural history of true DH. The suspicion of DH starts on clinical grounds.
Anca M, Chiriac, Pascal, Demoly
openaire +2 more sources
Poorly documented and often self-reported drug hypersensitivity (DH) is a frequent problem in daily clinical practice and has a considerable impact on prescription choices. Little is known about the natural history of true DH. The suspicion of DH starts on clinical grounds.
Anca M, Chiriac, Pascal, Demoly
openaire +2 more sources
Desensitization for drug allergy
Current Opinion in Allergy and Clinical Immunology, 2006Desensitization for drug allergy is the induction of temporary clinical unresponsiveness to drug antigens. Gradual reintroduction of small doses of drug antigen at fixed time intervals allows for the delivery of full therapeutic doses, protecting patients from anaphylaxis.
openaire +2 more sources
Immunology and Allergy Clinics of North America, 2014
Drugs are known triggers of anaphylaxis in patients with mastocytosis even to the association between drug anaphylaxis and mastocytosis does not appear frequently appear. Nevertheless, mast cell disorders might be ruled out in cases of severe systemic reactions. Careful examination of the skin should accompany measurement of basal serum tryptase levels.
Patrizia, Bonadonna, Carla, Lombardo
openaire +2 more sources
Drugs are known triggers of anaphylaxis in patients with mastocytosis even to the association between drug anaphylaxis and mastocytosis does not appear frequently appear. Nevertheless, mast cell disorders might be ruled out in cases of severe systemic reactions. Careful examination of the skin should accompany measurement of basal serum tryptase levels.
Patrizia, Bonadonna, Carla, Lombardo
openaire +2 more sources
Journal of the American Medical Association, 1955
An advertisement for a recent edition of the "Red Book," which lists all of the 140,000 medicaments handled by pharmacists and available to physicians for patients, states that "14,000 new drugs" were issued by drug manufacturers in 1953. In actuality, there were few really new drugs. The number given represents some truly introduced for the first time,
openaire +2 more sources
An advertisement for a recent edition of the "Red Book," which lists all of the 140,000 medicaments handled by pharmacists and available to physicians for patients, states that "14,000 new drugs" were issued by drug manufacturers in 1953. In actuality, there were few really new drugs. The number given represents some truly introduced for the first time,
openaire +2 more sources
Immunology and Allergy Clinics of North America, 2015
Most children with a history of penicillin allergy are labeled allergic and denied treatment with penicillin and sometimes other beta-lactam antibiotics. Most of these children never were or are no longer allergic to penicillin. Penicillin skin testing and oral challenge can identify patients who are not currently allergic, allowing them to be treated ...
openaire +2 more sources
Most children with a history of penicillin allergy are labeled allergic and denied treatment with penicillin and sometimes other beta-lactam antibiotics. Most of these children never were or are no longer allergic to penicillin. Penicillin skin testing and oral challenge can identify patients who are not currently allergic, allowing them to be treated ...
openaire +2 more sources
The Journal of Allergy and Clinical Immunology: In Practice
When approaching a case of apparent drug allergy, the consulting clinician should consider a broad differential diagnosis. This article presents a series of cases that could be commonly referred to an allergist for assessment as "drug allergy," however, a real diagnosis exists that mandates a different diagnostic and treatment strategy, including a ...
Jamie L, Waldron +4 more
openaire +2 more sources
When approaching a case of apparent drug allergy, the consulting clinician should consider a broad differential diagnosis. This article presents a series of cases that could be commonly referred to an allergist for assessment as "drug allergy," however, a real diagnosis exists that mandates a different diagnostic and treatment strategy, including a ...
Jamie L, Waldron +4 more
openaire +2 more sources