Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
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Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations. [PDF]
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Kappa-Opioid Receptor Antagonism Prolongs the Antidepressant Effects of Ketamine in Adult Mice with Depression-like Behavior Induced by Adolescent Chronic Unpredictable Stress. [PDF]
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Re-sedation using remimazolam anesthesia in patients with multiple injuries during recovery: a case report and literature review. [PDF]
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Antipsychotic drugs at 75: the past, present, and future of psychosis management. [PDF]
Br Med BullLyman M, McCutcheon RA.
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Neuromuscular block in paediatric patients undergoing airway management: a narrative review. [PDF]
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Antagonistic drug interactions protect commensal <i>Bacteroidaceae</i> from macrolides via an RND-type efflux pump. [PDF]
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