Results 291 to 300 of about 4,518,745 (345)

Dynamics of recovery and measure of drug antagonism; inhibition of smooth muscle by lysocithin and antihistaminics.

Journal of Pharmacology and Experimental Therapeutics, 1948
A method of preparation of lysocithin is described and its inhibitory effect upon the action of histamine, acetylcholine and KCl on the guinea pig gut studied.
M.Rocha E Silva, Wilson T. Beraldo
semanticscholar   +1 more source

[Drug antagonism].

Revue medicale de Bruxelles, 1993
The mechanisms responsible of either a loss of therapeutic efficiency or a beneficial cancellation of toxic phenomena are reviewed. References are specifically made to antagonists of anti-vitamin K, oral contraceptives, antihypertensive drugs and statin.
J, Sternon, D, Even-Adin
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Dopamine Antagonism and Antischizophrenic Potency of Neuroleptic Drugs

Nature New Biology, 1973
IT has been argued1–4 that ability to block central dopamine receptors is related to the therapeutic potency of neuroleptic drugs in schizophrenia. Two lines of evidence favour this hypothesis. First, dopamine antagonism probably underlies the “extrapyramidal” or Parkinsonian side effects of neuroleptic drugs5, and such side effects are a frequent ...
T J, Crow, C, Gillbe
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Harmine antagonism of drug-induced extra-pyramidal disturbances

Psychopharmacologia, 1964
An investigation was carried out on harmine as a possible anti-parkinson agent in reserpine, chloropromazine or encephalitis induced parkinsonism. Significantly better response to harmine was obtained in the patients with the reserpine-induced symptoms than in the other types.
B, Blum, H, Weizmann, G M, Simpson, D, Krasilowsky, I S, Kulcsar, H, Merskey   +5 more
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Conditioned taste aversion and cholinergic drugs: pharmacological antagonism

Pharmacology Biochemistry and Behavior, 1987
The effectiveness of drugs as unconditioned stimuli (UCSs) in the conditioned taste aversion (CTA) procedure may be influenced by specific pharmacological antagonism. The present studies examined the UCS effects of two carbamates, physostigmine salicylate (PS) and pyridostigmine bromide (PB), and three anticholinergic compounds, atropine methyl nitrate
J A, Romano, J M, King
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Sulpha drugs and its antagonism

The Indian Journal of Pediatrics, 1948
From the above experimental studies, and from the actual records we conclude that there is no necessity of an inference of the role of p-amino benzoic acid in the bacterial metabolism and how it is antagonised by the sulpha drugs. On the other hand we come to this conclusion from the results of direct observation that bacteria utilises oxygen from ...
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Antagonism of drug-induced pulsus alternans in dogs

American Journal of Physiology-Legacy Content, 1960
Pulsus alternans and pseudoalternans were produced in dogs anesthetized with pentobarbital by intravenous injections of moderate doses of one of several pharmacologic agents. Ventricular alternation was alleviated or abolished by a) drugs with positive inotropic action, b) drugs that reduced peripheral resistance, and c) drugs with antiarrhythmic ...
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Folic acid antagonism of sulfa drug treatments

Trends in Parasitology, 2002
Abstract Folic acid antagonizes the sulfa drug treatment of malaria. This antagonism has been mimicked in a yeast model system, where the growth inhibition by sulfa drugs can be confounded. In addition, yeast studies show that the inhibition is independent of folic acid utilization, suggesting that the antagonism occurs by an unexpected mechanism.
Ann M Bayly, Ian G Macreadie
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Qualitative Aspects of Drug Antagonism

1937
The relation between chemical structure and pharmacological action is a subject of notorious difficulty. It may be said that there are scarcely any general rules discernible and that every cell-drug system appears to be a law unto itself. In the case of drugs which have sharply specific actions, it is common to find that the activity even of optical ...
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Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies

Pharmacological Reviews, 2006
T. Chou
semanticscholar   +1 more source