Results 241 to 250 of about 776,039 (330)

Activism and Cancer Drug Approval [PDF]

Journal of Oncology Practice, 2007
openaire   +3 more sources

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval. [PDF]

PLoS Genet, 2019
King EA, Davis JW, Degner JF.
europepmc   +1 more source

Drug approval and research assessment: arguments for reform. [PDF]

J R Soc Med, 2016
Abbasi K.
europepmc   +1 more source

Regulatory Science and Drug Approval for Alcoholic and Nonalcoholic Steatohepatitis. [PDF]

Gastroenterology, 2016
Sanyal AJ, Miller V.
europepmc   +1 more source

Factors Affecting Drug-Development Strategies in Asian Global Clinical Trials for Drug Approval in Japan. [PDF]

Clin Transl Sci, 2018
Asano K, Uyama Y, Tohkin M.
europepmc   +1 more source

Evaluation of the glottic surface dose in three‐dimensional conformal radiotherapy for early‐stage glottic cancer using a treatment planning system

Journal of Applied Clinical Medical Physics, EarlyView.
ABSTRACT Background In radiotherapy for early‐stage glottic cancer, evaluating the target surface dose at the glottic air–tissue boundary is crucial, as buildup effect can cause underdosing. The accuracy of dose evaluation in the surrounding tissues is affected by both the dose calculation algorithms and the accuracy of the Hounsfield unit values in ...
Yuki Saito, Takahiro Kanehira, Takahito Yuki, Miyako Myojin   +3 more
wiley   +1 more source

Drug approval status and recommendations for listing on public formularies: a Canadian cohort analysis. [PDF]

BMJ Open, 2017
Lexchin J.
europepmc   +1 more source

Enhanced dose prediction for head and neck cancer artificial intelligence‐driven radiotherapy based on transfer learning with limited training data

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Training deep learning dose prediction models for the latest cutting‐edge radiotherapy techniques, such as AI‐based nodal radiotherapy (AINRT) and Daily Adaptive AI‐based nodal radiotherapy (DA‐AINRT), is challenging due to limited data.
Hui‐Ju Wang, Austen Maniscalco, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +5 more
wiley   +1 more source

A descriptive research: Exclusion from submitted clinical data package in the review process of new drug approval due to GCP violation in Japan. [PDF]

Contemp Clin Trials Commun, 2019
Asada R, Yoshimura K, Hattori K, Nonaka Y, Kasai H, Shimizu S.   +5 more
europepmc   +1 more source

Assessing proton plans with three different beam delivery systems versus photon plans for head and neck tumors

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare plan quality among photon volumetric modulated arc therapy (VMAT) and intensity‐modulated proton therapy (IMPT) with robustness using three different proton beam delivery systems with various spot size (σ) ranges: cyclotron‐generated proton beams (CPBs) (σ: 2.7–7.0 mm), linear accelerator proton beams (LPBs) (σ: 2.9–5.5 mm),
Tara Gray, Chieh‐Wen Liu, Saeed Ahmed, Anna Maria Kolano, Jeremy Donaghue, Shlomo Koyfman, Neil Woody, Shauna R. Campbell, Jonathan B. Farr, Ping Xia   +9 more
wiley   +1 more source