Results 61 to 70 of about 757,641 (252)
Strong Support For Sununu, Drugs Remain Most Important Problem Facing NH 5/9/17 [PDF]
, 2017 Governor Chris Sununu enjoys bipartisan approval of his job performance as well as increasing personal favorability among New Hampshire adults. A strong majority continue to believe overall the state is headed in the right direction, but for the first ...
Survey Center, UNH
core +1 more source
A review of the regulatory framework for personalized bacteriophages registration
Вопросы вирусологии, 2020 The increasing trend in antimicrobial resistance of pathogenic bacteria dictates the need for alternative solutions. Bacteriophages are bacterial viruses that kill their hosts during the lifecycle.
N. N. Landyshev +5 more
doaj +1 more source
Clinical and Translational Science, 2021 The current success rate of a drug candidate, from the beginning of the clinical trial to receiving marketing approval, is about 10%–20%, and it has not changed during the past few decades. Therefore, pharmaceutical companies are under pressure to select
Shingo Yamaguchi +2 more
doaj +1 more source
Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentation. [PDF]
, 2008 BackgroundPrevious studies of drug trials submitted to regulatory authorities have documented selective reporting of both entire trials and favorable results.
Bacchetti, Peter +2 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
In vitro toxicity model: Upgrades to bridge the gap between preclinical and clinical research
Biomolecules & Biomedicine, 2020 The Centers for Disease Control and Prevention (CDC) provides extensive data that indicate our need for drugs to maintain human population health. Despite the substantial availability of drugs on the market, many patients lack specific drugs.
Eneko Madorran +3 more
doaj +1 more source
Pharmacology Research & Perspectives, 2023 Recently, post‐marketing safety measures have been considered critical in Japan due to the globalization of drug development and the introduction of new drug approval systems.
Rieko Saito, Seiko Miyazaki
doaj +1 more source
Lack of Transparency in the Premarket Approval Process for Aquadvantage Salmon [PDF]
, 2013 After a lengthy premarket approval process, the Food and Drug Administration (FDA) has just deemed AquAdvantage Salmon, a fast-growing, genetically engineered salmon, safe for human consumption.
McEvilly, Michael P.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]
, 2020 Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie +9 more
core +1 more source