Results 141 to 150 of about 415,670 (364)
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Coarse-grain Molecular Dynamics Study of Fullerene Transport across a Cell Membrane [PDF]
arXiv, 2015 The study of the ability of drug molecules to enter cells through the membrane is of vital importance in the field of drug delivery. In cases where the transport of the drug molecules through the membrane is not easily accomplishable, other carrier molecules are used.
arxiv
یافتههای نوین در علوم زیستی, 2021 The aim of this study was to investigate the interaction modification of curcumin complex molecule (CUR) in beta- and gamma-cyclodextrin (β-CD and γ-CD) carriers with chitosan (CS) nanoparticles for targeted drug delivery and to compare their performance.
Nina Alizadeh, Shokufeh Malakzadeh
doaj
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Malaria vaccines and the new malaria agenda. [PDF]
, 2011 The development of an effective malaria vaccine has taken many decades, but there is now a good chance that the first malaria vaccine will be licensed within the next few years.
Greenwood, BM, Targett, GAT
core +1 more source
A Revision of the Bernoulli Equation as a Controller of the Fick's Diffusion Equation in Drug Delivery Modeling [PDF]
arXiv, 2019 Mathematical equations can be used as effectual tools in drug delivery systems modeling and are also highly helpful to have a theoretical understanding of controlled drug release and diffusion mechanisms. In this study we aim to present a mathematical combination between the Bernoulli equation and the Fick's equation as a diffusion controller in drug ...
arxiv
LIPOSOMES IN THERAPEUTIC AND PREVENTIVE MEDICINE: THE DEVELOPMENT OF THE DRUG‐CARRIER CONCEPT [PDF]
, 1978 Gregory Gregoriadis
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
A study of nanoparticles as a drug carrier on the wall of Stenosed Arteries [PDF]
, 2018 The influences of nanoparticles as drug carriers on the walls of stenosed arteries are presented. In this study, three nanoparticles namely Fe3O4 , TiO2 and Cu were used.
Abdulhameed, Mohammed +5 more
core
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source