Results 171 to 180 of about 793,336 (333)

An open-source screening platform accelerates discovery of drug combinations. [PDF]

Nat Commun
Wright WC, Pan M, Phelps GA, Low J, Currier D, Sanjali A, Trotter M, Hwang J, Chapple RH, Liu X, Bennett D, Zhang Y, Lee RE, Chen T, Geeleher P.   +14 more
europepmc   +1 more source

Synergistic Anticancer Activity of Topotecan— Cyclin-Dependent Kinase Inhibitor Combinations against Drug-Resistant Small Cell Lung Cancer (SCLC) Cell Lines

, 2013
Gerhard Hamilton, Lukas Klameth Ulrike Olszewski, Ernst Ulsperger, Klaus Geißler   +3 more
openalex   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Editorial: Innovative drug combinations for enhanced solid tumor treatment efficacy. [PDF]

Front Oncol
Damia G, Broggini M.
europepmc   +1 more source

Boolean network-based identification of optimal drug combinations for prostate cancer

Pranabesh Bhattacharjee, Addanki P. Kumar, Aniruddha Datta   +2 more
openalex   +1 more source

Comparison of methodologies for synergism testing of drug combinations against resistant strains of Pseudomonas aeruginosa [PDF]

, 1996
Diane M. Cappelletty, Michael J. Rybak
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Corrigendum: Differential effects of clopidogrel and/or aspirin on the healing of tooth extraction wound bone tissue

Frontiers in Physiology
Jiaping Wang, Juan Lin, Xin Song, Mengting Wang, Yan Chen, Ning Luo, Xin Wu   +6 more
doaj   +1 more source

SynergyImage: image-based model for drug combinations synergy score prediction. [PDF]

BMC Bioinformatics
Mehrabani M, Lakizadeh A, Fotuhi Siahpirani A, Masoudi-Nejad A.   +3 more
europepmc   +1 more source

Synergistic drug combinations designed to fully suppress SARS-CoV-2 in the lung of COVID-19 patients

, 2022
Davide De Forni, Barbara Poddesu, Giulia Cugia, James G. Chafouleas, Julianna Lisziewicz, Franco Lori   +5 more
openalex   +2 more sources