Results 201 to 210 of about 737,831 (320)

Combinations of drugs in the treatment of acute leukemias.

, 1965
Zubrod Cg
openalex  

A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS [PDF]

, 2008
Gordon Gilbert, Ying Kuen Cheung, Bruce Levin, Howard Andrews, Carolyn Doorish, Robert B. MacArthur, Jacqueline Montes, Kate Bednarz, Julaine Florence, Julie Rowin, Khrista Boylan, Tahseen Mozaffar, Rup Tandan, Hiroshi Mitsumoto, Elizabeth A. Kelvin, John Chapin, Richard Bedlack, Michael H. Rivner, Leo McCluskey, Alan Pestronk, Michael C. Graves, Eric J. Sorenson, Richard J. Barohn, Jerry M. Belsh, Jau-Shin Lou, Todd Levine, David Saperstein, Robert G. Miller, Stephen N. Scelsa, The Combination Drug Selection Tria   +29 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

The association of prescriber prominence in a shared-patient physician network with their patients receipt of and transitions between risky drug combinations. [PDF]

Appl Netw Sci
O'Malley AJ, Meara E, Morden NE, Moen EL, Ran X.   +4 more
europepmc   +1 more source

Systematic analysis of drug combinations against Gram-positive bacteria. [PDF]

Nat Microbiol, 2023
Cacace E, Kim V, Varik V, Knopp M, Tietgen M, Brauer-Nikonow A, Inecik K, Mateus A, Milanese A, Mårli MT, Mitosch K, Selkrig J, Brochado AR, Kuipers OP, Kjos M, Zeller G, Savitski MM, Göttig S, Huber W, Typas A.   +19 more
europepmc   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

The Management of Treatment‐Experienced HIV‐Infected Patients: New Drugs and Drug Combinations [PDF]

, 2008
Lucy E. Wilson, Joel E. Gallant
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Integrated analysis of CD30 detection methodologies and synergistic drug combinations for optimizing brentuximab vedotin therapy in lymphoma. [PDF]

Clin Exp Med
Ye M, Wang T, Song Z, Liu X, Liu P, Zhang L, Tang G, He M, Liu N, Yang J.   +9 more
europepmc   +1 more source

In vitro Chemosensitivity of Hepatocellular Carcinoma for Hepatic Arterial Infusion Chemotherapy Using the MTT Assay with the Combinations of Antitumor Drugs

, 2004
Satoshi Furukawa
openalex   +2 more sources