Results 221 to 230 of about 943,135 (348)

Development of drug resistance in patients receiving combinations of zidovudine, didanosine and nevirapine

, 2001
Brian Conway, Mark A. Wainberg, David B. Hall, Marianne Harris, Peter Reiss, David A. Cooper, Stefano Vella, R. L. Curry, Patrick Robinson, Joep M. A. Lange, Julio Montaner   +10 more
openalex   +1 more source

Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison [PDF]

, 2007
A. Ratcliff, Hadjar Siswantoro, Enny Kenangalem, R. Maristela, R. M. Wuwung, Ferdinand Laihad, E. P. Ebsworth, N. M. Anstey, Emiliana Tjitra, Ric N. Price   +9 more
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

A new method for concomitant evaluation of drug combinations for their antimicrobial properties. [PDF]

MethodsX
Rizvi SA, Chowdhury KF, Borsetto C, Travis ER, Saif M, Ahmed V, Carter LJ, Ahmad I, McNally A, Haq QMR.   +9 more
europepmc   +1 more source

Combinations of drugs in the treatment of acute leukemias.

, 1965
Zubrod Cg
openalex  

The Efficacy of Potent Anti-retroviral Drug Combinations Tested in a Murine Model of HIV-1 Encephalitis

, 2001
Jenae Limoges, Larisa Y. Poluektova, Winai Ratanasuwan, Jennifer Rasmussen, Marina Zelivyanskaya, Daniel McClernon, E. Randall Lanier, Howard E. Gendelman, Yuri Persidsky   +8 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Cancer Cell's Achilles Heels: Considerations for Design of Anti-Cancer Drug Combinations. [PDF]

Int J Mol Sci
Gahramanov V, Vizeacoumar FS, Morales AM, Bonham K, Sakharkar MK, Kumar S, Vizeacoumar FJ, Freywald A, Sherman MY.   +8 more
europepmc   +1 more source

The Management of Treatment‐Experienced HIV‐Infected Patients: New Drugs and Drug Combinations [PDF]

, 2008
Lucy E. Wilson, Joel E. Gallant
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source