Results 41 to 50 of about 2,669,018 (297)

NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning. [PDF]

open access: yesPLoS Computational Biology, 2016
Fungal infection has become one of the leading causes of hospital-acquired infections with high mortality rates. Furthermore, drug resistance is common for fungus-causing diseases.
Xing Chen   +5 more
doaj   +1 more source

Long-term drug use and polypharmacy among the elderly population in the Republic of Srpska, Bosnia and Herzegovina [PDF]

open access: yesVojnosanitetski Pregled, 2016
Background/Aim. Prescription of drugs is a fundamental care component of the elderly. Elderly patients often take multiple drugs, and it is known that polypharmacy may lead to drug interactions and adverse events.
Marković-Peković Vanda, Škrbić Ranko
doaj   +1 more source

Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations

open access: yesViruses, 2022
Long-acting (LA) anti-HIV regimens show promise for increasing dosing intervals and consequently, improving the patients’ quality of life. The first FDA-approved LA therapy is Cabenuva, which comprises rilpivirine (a non-nucleoside reverse transcriptase ...
Maria E. Cilento   +3 more
doaj   +1 more source

DCDB: Drug combination database [PDF]

open access: yesBioinformatics, 2009
Abstract Summary: Rapid advances in pharmaceutical sciences have brought ever-increasing interests in combined therapies for better clinical efficacy and safety, especially in cases of complicated and refractory diseases. Innovative experimental technologies and theoretical frameworks are being actively developed for multicomponent drug ...
Yanbin Liu   +3 more
openaire   +3 more sources

Combinations of drugs in the Treatment of Obesity [PDF]

open access: yesPharmaceuticals, 2010
Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use.
Halpern, Bruno   +6 more
openaire   +3 more sources

Synergistic and antagonistic drug combinations depend on network topology. [PDF]

open access: yesPLoS ONE, 2014
Drug combinations may exhibit synergistic or antagonistic effects. Rational design of synergistic drug combinations remains a challenge despite active experimental and computational efforts.
Ning Yin   +5 more
doaj   +1 more source

Inhibitory Mechanisms of DHA/CQ on pH and Iron Homeostasis of Erythrocytic Stage Growth of Plasmodium falciparum

open access: yesMolecules, 2019
Malaria is an infectious disease caused by Plasmodium group. The mechanisms of antimalarial drugs DHA/CQ are still unclear today. The inhibitory effects (IC50) of single treatments with DHA/CQ or V-ATPase inhibitor Baf-A1 or combination treatments by DHA/
Tian Tang   +6 more
doaj   +1 more source

Anthelmintic resistance of gastrointestinal nematodes in cattle in Brazil and Argentina - current status and global perspectives [PDF]

open access: yesRevista Brasileira de Parasitologia Veterinária
This review outlines the current state of anthelmintic resistance (AHR) of gastrointestinal nematodes (GINs) among cattle in Argentina and Brazil, emphasizing the economic repercussions, animal health and welfare. The analysis explores factors associated
Fernando de Almeida Borges   +5 more
doaj   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

open access: yes, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Data Record 1: Drug ingredient combinations: 1-drug

open access: yes, 2017
Data Record 1: Drug ingredient combinations: 1 ...
Shah, Nigam H.   +3 more
core   +1 more source

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