Results 21 to 30 of about 419,272 (285)
Candyflipping and Other Combinations: Identifying Drug–Drug Combinations from an Online Forum
Frontiers in Psychiatry, 2018 Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades.
Michael Chary, David Yi, Alex F. Manini
doaj +1 more source
Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]
, 2014 This work was supported by grants from Breakthrough Breast Cancer and Scottish Funding Council (SRDG), and personal support to Alexey Goltsov from Scottish Informatics and Computer Science Alliance (SICSA) and to James Bown from The Northwood Trust.Drug ...
Bown, James +22 more
core +1 more source
Eradication of Drug-Tolerant Mycobacterium tuberculosis 2022: Where We Stand
Microorganisms, 2023 The lungs of tuberculosis (TB) patients contain a spectrum of granulomatous lesions, ranging from solid and well-vascularized cellular granulomas to avascular caseous granulomas.
Alessio Lanni +3 more
doaj +1 more source
Bifunctional antibiotic hybrids: A review of clinical candidates
Frontiers in Pharmacology, 2023 Antibiotic resistance is a top threat to human health and a priority across the globe. This problematic issue is accompanied by the decline of new antibiotics in the pipeline over the past 30 years.
Augustine Jing Jie Koh +6 more
doaj +1 more source
Dynamical Synergy of Drug Combinations during Cancer Chemotherapy
, 2022 Synergistic drug combinations often provide effective strategies to increase treatment efficacy and, during therapy, it is a time-dependent process. Data for colorectal and lung cancer in vivo were used for the phenomenological study of dynamical synergy
Martorana, Emanuele +5 more
core +1 more source
Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug [PDF]
, 2013 BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Speich Benjamin +17 more
core +1 more source
Journal of Nepal Medical Association, 2021 Introduction: To establish appropriate health care services in developing countries, rationalization of drug use holds utmost importance. Drug use patterns can be found out using Core Indicators of the World Health Organisation in collaboration with the ...
Jyoti Tara Manandhar Shrestha +4 more
doaj +1 more source
Combinations of drugs in the Treatment of Obesity [PDF]
Pharmaceuticals, 2010 Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use.
Marcio C. Mancini +6 more
openaire +3 more sources
DCDB: Drug combination database [PDF]
Bioinformatics, 2009 Abstract Summary: Rapid advances in pharmaceutical sciences have brought ever-increasing interests in combined therapies for better clinical efficacy and safety, especially in cases of complicated and refractory diseases. Innovative experimental technologies and theoretical frameworks are being actively developed for multicomponent drug ...
Yanbin Liu +3 more
openaire +2 more sources
Viribus Unitis: Drug Combinations as a Treatment Against COVID-19
, 2020 The opportunities that may be provided by synergistic antiviral action of drugs for battling SARS-CoV2 are currently underestimated. Modern AI technologies realized as text, data, and knowledge mining and analytics tools provide the researchers with ...
Alexey, Zakharov, Eugene, Muratov
core +1 more source