Results 11 to 20 of about 398,363 (249)
Candyflipping and Other Combinations: Identifying Drug–Drug Combinations from an Online Forum
Frontiers in Psychiatry, 2018 Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades.
Michael Chary, David Yi, Alex F. Manini
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Understanding the Clinical Use of Levosimendan and Perspectives on its Future in Oncology
Biomolecules, 2023 Drug repurposing, also known as repositioning or reprofiling, has emerged as a promising strategy to accelerate drug discovery and development. This approach involves identifying new medical indications for existing approved drugs, harnessing the ...
Eduarda Ribeiro, Nuno Vale
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Eradication of Drug-Tolerant Mycobacterium tuberculosis 2022: Where We Stand
Microorganisms, 2023 The lungs of tuberculosis (TB) patients contain a spectrum of granulomatous lesions, ranging from solid and well-vascularized cellular granulomas to avascular caseous granulomas.
Alessio Lanni +3 more
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Bifunctional antibiotic hybrids: A review of clinical candidates
Frontiers in Pharmacology, 2023 Antibiotic resistance is a top threat to human health and a priority across the globe. This problematic issue is accompanied by the decline of new antibiotics in the pipeline over the past 30 years.
Augustine Jing Jie Koh +6 more
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Journal of Nepal Medical Association, 2021 Introduction: To establish appropriate health care services in developing countries, rationalization of drug use holds utmost importance. Drug use patterns can be found out using Core Indicators of the World Health Organisation in collaboration with the ...
Jyoti Tara Manandhar Shrestha +4 more
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Network-based prediction of drug combinations
Nature Communications, 2019 Combination therapy holds great promise, but discovery remains challenging. Here, the authors propose a method to identify efficacious drug combinations for specific diseases, and find that successful combinations tend to target separate neighbourhoods ...
Feixiong Cheng +2 more
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Combinations of drugs in the Treatment of Obesity [PDF]
Pharmaceuticals, 2010 Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use.
Bruno Halpern +6 more
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DCDB: Drug combination database [PDF]
Bioinformatics, 2009 Abstract Summary: Rapid advances in pharmaceutical sciences have brought ever-increasing interests in combined therapies for better clinical efficacy and safety, especially in cases of complicated and refractory diseases. Innovative experimental technologies and theoretical frameworks are being actively developed for multicomponent drug ...
Yanbin Liu +3 more
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Market research of medicinal products which are used in cardiological diseases treatment
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Aim of the study is to carry out market research of medicinal products which are used in cardiological diseases treatment. Materials and methods.
O. S. Kukhtenko +2 more
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Investigating therapeutic efficacy of dacarbazine and temozolomide, alone and in combination with BRAF(V600E) siRNA in A375 human melanoma cell line [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Melanoma is one of the most aggressive and deadly skin cancers. Despite advances, effective melanoma treatment is challenging, often requiring a shift from individual therapies to combination approaches.
Fatemeh Tabandeh +3 more
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