Results 61 to 70 of about 769,426 (246)

Successful treatment of polymedicamentous poisoning with metoprolol, diltiazem and cilazapril [PDF]

open access: yesVojnosanitetski Pregled, 2009
Introduction. Poisoning caused by drugs with cardiodepressive effects is an urgent condition in medicine which is associated with high mortality rate regardless of modern therapeutic methods.
Radovanović Milan R.   +2 more
doaj   +1 more source

Discovery of Natural Products With Antifungal Potential Through Combinatorial Synergy

open access: yesFrontiers in Microbiology, 2022
The growing prevalence of antifungal drug resistance coupled with the slow development of new, acceptable drugs and fungicides has raised interest in natural products (NPs) for their therapeutic potential and level of acceptability.
Catheryn R. Augostine, Simon V. Avery
doaj   +1 more source

Identification and Tracking of Antiviral Drug Combinations

open access: yesViruses, 2020
Combination therapies have become a standard for the treatment for HIV and hepatitis C virus (HCV) infections. They are advantageous over monotherapies due to better efficacy, reduced toxicity, as well as the ability to prevent the development of ...
Aleksandr Ianevski   +25 more
doaj   +1 more source

Changes in kidney function in a population with essential hypertension in real life settings [PDF]

open access: yes, 2017
Introduction. Hypertension has been identified as one of the commonest modifiable determinants for chronic kidney disease progression. A variety of antihypertensive drugs are available and their effect on kidney function has been investigated by a ...
Haidich, Anna-Bettina   +6 more
core  

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

open access: yes, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew   +5 more
core   +1 more source

A Bayesian seamless phase I-II trial design with two stages for cancer clinical trials with drug combinations

open access: yes, 2020
The use of drug combinations in clinical trials is increasingly common during the last years since a more favorable therapeutic response may be obtained by combining drugs.
Jiménez, José L.   +2 more
core   +1 more source

Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]

open access: yes, 2003
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core   +1 more source

PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUG COMBINATIONS USE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To pursue pharmacoeconomic analysis of two drug combinations of ACE inhibitor (enalapril) and diuretic.Material and methods. Patients with arterial hypertension degree 2 and diabetes mellitus type 2 without ischemic heart disease (n=56) were ...
E. I. Tarlovskaya   +2 more
doaj   +3 more sources

Antinociceptive Effects of Sinomenine Combined With Ligustrazine or Paracetamol in Animal Models of Incisional and Inflammatory Pain

open access: yesFrontiers in Physiology, 2021
The management of postoperative and inflammatory pain has been a pressing challenge in clinical settings. Sinomenine (SN) is a morphinan derived alkaloid with remarkable analgesic properties in various kinds of pain models.
Tianle Gao   +12 more
doaj   +1 more source

Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro [PDF]

open access: yes, 2017
Multi-drug strategies have been attempted to prolong the efficacy of existing antibiotics, but with limited success. Here we show that the evolution of multi-drug-resistant Escherichia coli can be manipulated in vitro by administering pairs of ...
Cronin, Leroy   +5 more
core   +1 more source

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