Results 101 to 110 of about 27,194 (296)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Senate Bill relating to the compounding of a drug or device by a pharmacist.

, 2007
Bill introduced by the Texas Senate relating to the compounding of a drug or device by a ...
Texas. Legislature. Senate.
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Comparison of solvent casting and spray casting method on compounding of an orally disintegrating film containing amlodipine besylate

, 2022
The amlodipine besylate tablet is one of the most highly prescribed medicines to manage hypertension in the geriatric population. However, the difficulty of swallowing tablets due to problems like dysphagia, fear of choking, and odynophagia has been ...
Helal Uddin, A.B.M., Janakiraman, Ashok Kumar Janakiraman, Sarker, Zaidul Islam, Ruslan, Mohamad Fariz Haiqal, Long, Chiau Ming, Liew, Kai Bin   +5 more
core  

Recommendations on training objectives and staff qualification for the manual preparation of capsules in pharmacy

Pharmaceutical Technology in Hospital Pharmacy
Training and certification of personnel in capsule preparation are essential procedures, overseen by the pharmacist who delegates these tasks. These procedures aim not only to ensure the efficacy and safety of operations but also to establish a clear ...
Marçon Frédéric, Lagarce Frédéric, Roland Isabelle, Brossard Denis, Merienne Camille, Chennell Philip, d’Huart Elise, Briot Thomas, Carrez Laurent, Podilsky Gregory, Rohrbach Pascal, Lannoy Damien, Storme Thomas, Guerrault-Moro Marie Noelle, Soulairol Ian, Crauste-Manciet Sylvie   +15 more
doaj   +1 more source

Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?

Pharmaceuticals
There are more than 170 known species of non-tuberculous mycobacteria, and some are responsible for serious diseases in people infected with them. One of these is Buruli ulcers, a neglected tropical disease endemic in more than 33 countries and caused by
Maria Sebti, Arnaud Schweitzer-Chaput, Salvatore Cisternino, Mélanie Hinterlang, Dimitri Ancedy, Sandrine Lam, Sylvain Auvity, Camille Cotteret, Olivier Lortholary, Joël Schlatter   +9 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Workflow evaluation of environmental contamination with hazardous drugs during compounding and administration in an UK hospital

Introduction: Exposure of healthcare workers to hazardous drugs may result in adverse health effects underscoring the importance of validating working procedures and safety precautions to minimise the risk.
Sessink, Paul J. M., Cameron, Lisa T., Campbell, Karen, Barry, Beverley, Kirkness, Tessa, Dunbar, Lisa   +5 more
core   +1 more source

Paediatric orodispersible lozenges produced by moulding process: quality and stability control

Pharmaceutical Technology in Hospital Pharmacy
Active pharmaceutical ingredients for paediatric patients are formulated at hospital pharmacy services and compounding pharmacies when they are not commercially available.
Magariños-Triviño María, Monzón-Rodríguez Cecilia, Caiazzo-Lima José Andrés, Santoveña-Estévez Ana, Fariña José B.   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Regulatory Gaps in Drug Compounding: Implications for Patient Safety, Innovation, and Fraud

, 2019
Drug compounding is the practice of mixing, combining, or altering drug ingredients to create a product that meets the medical needs of a patient whose needs cannot otherwise be met with commercially-available products.
Shepherd, Joanna
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