Results 111 to 120 of about 1,831,464 (254)

Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?

open access: yesPharmaceuticals
There are more than 170 known species of non-tuberculous mycobacteria, and some are responsible for serious diseases in people infected with them. One of these is Buruli ulcers, a neglected tropical disease endemic in more than 33 countries and caused by
Maria Sebti   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Drug use among secondary school students, New South Wales, 1986

open access: yes, 2019
This survey has a number of objectives: to monitor the nature and extent of alcohol and other drug use; to provide data from which the need for social policy and educational initiatives could be determined; and to provide background data to facilitate ...
NSW Drug and Alcohol Authority
core   +1 more source

Recommendations on training objectives and staff qualification for the manual preparation of capsules in pharmacy

open access: yesPharmaceutical Technology in Hospital Pharmacy
Training and certification of personnel in capsule preparation are essential procedures, overseen by the pharmacist who delegates these tasks. These procedures aim not only to ensure the efficacy and safety of operations but also to establish a clear ...
Marçon Frédéric   +15 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions.

open access: yes, 2018
Three brands of levothyroxine tablets are currently available in New Zealand (Eltroxin, Mercury Pharma, Synthroid) for extemporaneous compounding into suspensions.
Lin, S-W   +10 more
core  

Paediatric orodispersible lozenges produced by moulding process: quality and stability control

open access: yesPharmaceutical Technology in Hospital Pharmacy
Active pharmaceutical ingredients for paediatric patients are formulated at hospital pharmacy services and compounding pharmacies when they are not commercially available.
Magariños-Triviño María   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The factors influencing compounding pharmacy extemporaneous drug formulation. Analysis of errors in 1st form prescriptions in compounding pharmacy. [PDF]

open access: yes, 2016
Aim: to analyze the factors influencing compounding pharmacy extemporaneous drug fomulation and an overview of the most common errors in writing 1st form prescriptions. Tasks: 1. Rate extemporaneous drug production regulation and formulation in Lithuania
Kavaliauskaitė, Eglė
core  

Hard Gelatin Capsules Compounded and Dispersed in Water in Pediatrics: Real Versus Theoretical Dose Administered

open access: yesPharmaceuticals
Background: In pediatric practice, dose individualization often requires the manipulation of solid oral dosage forms, such as dispersing capsules in water and administering only part of the volume.
Romain Paoli-Lombardo   +8 more
doaj   +1 more source

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