Modelling the consequences of targeted selective treatment strategies on performance and emergence of anthelmintic resistance amongst grazing calves [PDF]
The development of anthelmintic resistance by helminths can be slowed by maintaining refugia on pasture or in untreated hosts. Targeted selective treatments (TST) may achieve this through the treatment only of individuals that would benefit most from ...
Berk, Zoe +3 more
core +2 more sources
A genome-wide portrait of pervasive drug contaminants [PDF]
AbstractUsing a validated yeast chemogenomic platform, we characterized the genome-wide effects of several pharmaceutical contaminants, including three N-nitrosamines (NDMA, NDEA and NMBA), two related compounds (DMF and 4NQO) and several of their metabolites. A collection of 4800 non-essential homozygous diploid yeast deletion strains were screened in
Joseph Uche Ogbede +2 more
openaire +3 more sources
Presence of antimicrobial cocktails in the hydrological cycles is of interest because of their potential to mediate antimicrobial resistance within the natural environment.
P. Kairigo +4 more
semanticscholar +1 more source
Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE +9 more
core +2 more sources
Evaluation of two closed-system drug transfer device in the antineoplastic drug elaboration process [PDF]
Objective: to assess the impact of two closed-system drug transfer device on the local and environmental contamination and preparation times in the process of preparation of parenteral chemotherapy compared to the standard system.
Sandra Gómez-Álvarez +4 more
doaj +1 more source
Genome-based analysis of infrequent Salmonella serotypes through the Thai pork production chain
Salmonella is a prevalent zoonotic foodborne pathogen. Swine and pork are implicated as important sources of salmonellosis in humans. In Chiang Mai and Lamphun Provinces in northern Thailand, there has been a high prevalence of Salmonella persistence for
Thanaporn Eiamsam-ang +4 more
doaj +1 more source
Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course [PDF]
Objective. To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. Design.
Almoazen +9 more
core +2 more sources
Enzymatic digestion and selective quantification of underivatised [delta]9-tetrahydrocannabinol and cocaine in human hair using gas chromatography-mass spectrometry. [PDF]
Gas chromatography-mass spectrometric (GC-MS) methods for drug analysis routinely employ derivatising reagents. The aim of this paper was to develop a method for the analysis of two recreational drugs, delta-9-tetrahydrocannabinol ([delta](9)-THC) and ...
Barker, James +3 more
core +3 more sources
Drug Contamination of Multi-dose Vials
R. M. SMITH, J. A. YOUXC, A. MANIXEIM
openaire +2 more sources
Nitrosodimethylamine impurities in metformin drug products: Physician insight
Metformin is a high-dose antidiabetic drug and most widely used first-line therapeutic agent for the management of type 2 diabetes mellitus (T2DM).
Chetan Doshi +4 more
doaj +1 more source

