Results 51 to 60 of about 411,025 (355)

Arsenic exposure and outcomes of antimonial treatment in visceral leishmaniasis patients in bihar, India:a retrospective cohort study [PDF]

, 2015
Funding: This work was supported by a Clinical PhD Fellowship to MRP (090665) and a Principal Research Fellowship to AHF (079838) from the Wellcome Trust (http://www.wellcome.ac.uk).
A Llanos-Cuentas, A Rahman, Alan H. Fairlamb, Albert Picado, Andrea Raab, CP Thakur, D Chakraborti, Dipankar Chakraborti, E Hasker, E Hassan, E van den Bogaart, F Chappuis, F Chappuis, F Chappuis, G Madalosso, G Matlashewski, J Alvar, Joerg Feldmann, Joris Menten, KR Hess, M Boelaert, M Vanaerschot, M Vanaerschot, Marleen Boelaert, Meghan R. Perry, MJ Sampaio, ML Erickson, MR Perry, MR Perry, N Sohel, NL Dangleben, P Ravenscroft, Philippe Büscher, PJ Guerin, PM Kaye, PN Williams, S Dey, S Rijal, S Rijal, S Sundar, S Sundar, S Sundar, S Wyllie, Shyam Sundar, SL Croft, Vijay K. Prajapati, Y Mueller, Z Cheng   +47 more
core   +4 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Occupational Exposure to Antineoplastic Drugs: Identification of Job Categories Potentially Exposed throughout the Hospital Medication System

Safety and Health at Work, 2011
Objectives: Studies examining healthcare workers’ exposure to antineoplastic drugs have focused on the drug preparation or drug administration areas. However, such an approach has probably underestimated the overall exposure risk as the drugs need to be ...
Chun-Yip Hon, Kay Teschke, Prescillia Chua, Scott Venners, Lynne Nakashima   +4 more
doaj   +1 more source

Medicine recalls in Saudi Arabia: a retrospective review of drug alerts (January 2010–January 2019)

Future Journal of Pharmaceutical Sciences, 2020
Background A new incidence of a substandard medicinal product is discovered weekly as stated by the World Health Organization (WHO) around the world. After discovering an incidence of a substandard medicinal product, a drug recall announced to remove the
Bushra T. AlQuadeib, Iman M. Alfagih, Ameera H. Alnahdi, Shadia M. Alharbi, Rawan A. Al-ahmari   +4 more
doaj   +1 more source

Microbial Contamination of Percutaneous Endoscopic Gastrostomy Tube and Nasogastric Tube with Drug-Resistant Bacteria.

Ann Nutr Metab
Kanamori S, Koya H, Kurata N, Ishino K.
europepmc   +2 more sources

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study. [PDF]

PLoS ONE, 2016
The objective of this randomized, prospective and controlled study was to investigate the ability of a closed-system transfer device (CSTD; BD-Phaseal) to reduce the occupational exposure of two isolators to 10 cytotoxic drugs and compare to standard ...
Nicolas Simon, Michèle Vasseur, Marine Pinturaud, Marion Soichot, Camille Richeval, Luc Humbert, Michèle Lebecque, Ousseini Sidikou, Christine Barthelemy, Pascal Bonnabry, Delphine Allorge, Bertrand Décaudin, Pascal Odou   +12 more
doaj   +1 more source

Assessment of degree of risk from sources of microbial contamination in cleanrooms; 2: surfaces and liquids [PDF]

, 2015
The degree of risk from microbial contamination of manufactured products in healthcare cleanrooms has been assessed in a series of three articles. The first article discussed airborne sources, and this second article considers surface contact and ...
Eaton, T., Whyte, W.
core  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source