Results 71 to 80 of about 1,750,852 (307)

Romantic love v.s. drug addiction may inspire a new treatment for addiction

open access: yesFrontiers in Psychology, 2016
Drug addiction is a complex neurological dysfunction induced by recurring drug intoxication. Strategies to prevent and treat drug addiction constitute a topic of research interest.
Zhiling Zou   +7 more
doaj   +1 more source

Alternative strategies to prevent and control endoparasite diseases in organic sheep and goat farming systems – a review of current scientific knowledge [PDF]

open access: yes, 2006
Infestation with gastro-intestinal nematodes in small ruminants can cause server economic losses and endanger animal welfare. The development of organic farming systems, the increased public awareness for drug residues in agricultural products and the ...
Rahmann, Gerold, Seip, Hannah
core  

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

open access: yes, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O.   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Biofeedback in the prophylactic treatment of medication overuse headache: a pilot randomized controlled trial [PDF]

open access: yes, 2016
Background: Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the need to manage chronic headache by using integrated biobehavioral approaches.
Cevoli, Sabina   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein degradation: expanding the toolbox to restrain cancer drug resistance

open access: yesJournal of Hematology & Oncology, 2023
Despite significant progress in clinical management, drug resistance remains a major obstacle. Recent research based on protein degradation to restrain drug resistance has attracted wide attention, and several therapeutic strategies such as inhibition of
Hui Ming   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

First-line anti-tubercular drug resistance of Mycobacterium tuberculosis in IRAN: a systematic review

open access: yesFrontiers in Microbiology, 2016
Background: The spread of drug-resistant tuberculosis (TB) is one of the major public health problems in the world. Surveillance of anti-TB drug resistance is important for monitoring of TB control strategies.
Babak Pourakbari   +3 more
doaj   +1 more source

Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs

open access: yesPharmaceuticals, 2022
The processes of solubilization and controlled release of drugs that are poorly soluble in water are highly relevant in drug preformulation studies in pharmaceutical development [...]
openaire   +3 more sources

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