Results 51 to 60 of about 1,750,852 (307)

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Transmission dynamics for Methicilin-resistant Staphalococous areus with injection drug user

BMC Infectious Diseases, 2018
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen resistance to antibiotics including methicillin. The resistance first emerged in 1960 in a healthcare setting only after two years of using methicillin as a viable ...
Rebekah Wagner, Folashade B. Agusto
doaj   +1 more source

Controlling the shape of membrane protein polyhedra

, 2017
Membrane proteins and lipids can self-assemble into membrane protein polyhedral nanoparticles (MPPNs). MPPNs have a closed spherical surface and a polyhedral protein arrangement, and may offer a new route for structure determination of membrane proteins ...
Haselwandter, Christoph A., Kahraman, Osman, Li, Di   +2 more
core   +1 more source

Assessment and Management of Hypertension among Patients on Peritoneal Dialysis [PDF]

, 2019
Approximately 7%-10% of patients with ESKD worldwide undergo peritoneal dialysis (PD) as kidney replacement therapy. The continuous nature of this dialytic modality and the absence of acute shifts in pressure and volume parameters is an important ...
Agarwal, Rajiv, Georgianos, Panagiotis I., Liakopoulos, Vassilios, Vaios, Vasilios   +3 more
core   +1 more source

Optimal control strategies for mitigating drug addiction: A mathematical modeling approach

Results in Control and Optimization
Drug addiction is widely recognized as a complex social issue influenced by various socio-economic and environmental factors. This study addresses the dynamics of drug addiction through a mathematical modeling approach, integrating epidemiological ...
Mostofa Kamal, Mostak Ahmed, Md. Abu Hanif Sarkar   +2 more
doaj   +1 more source

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari, Alimuddin Zumla, Armand, Axelsson-Robertson, Banada, Ben Marais, Betsou, Blakemore, Boehme, Boehme, Cattamanchi, Chow, Cuevas, Cuevas, Cuevas, Cuevas, Diel, Dowdy, Dye, European Centre for Disease Prevention and Control, Ferrara, Giovanni-Batista Migliori, Giuseppe Pantaleo, Green, Harari, Helb, Helen Cox, Hillemann, Hohn, Ibrahim Abubakar, Jeremiah Chakaya, John, Justin O’Grady, Karin Weyer, Keeler, Kemp, Kunnath-Velayudhan, Lawn, Lawn, Lawn, Lawn, Lawn, Lemaire, Lin, Ling, Liu, Long, Lucica Ditui, Lynn Zijenah, Mann, Marais, Marais, Marais, Marais, Marco Schito, Markus Maeurer, Marlowe, Martin P. Grobusch, Martina Casenghi, Matthew Bates, McNerney, Michael Hoelscher, Michel Pletschette, Minion, Moore, Morris, Mwaba, Nathan Ford, Nathanson, National Institute for Health and Clinical Excellence, Nicol, Nicol, Oberhelman, O’Grady, Peter, Peter Mwaba, Peter S. Kim, Rifat Atun, Rose, Ruth McNerney, S. Bertel Squire, Samana Schwank, Sester, Shah, Soumya Swaminathan, Squire, Squire, Steingart, Steingart, Steingart, Steve Lawn, Storla, Temple, Theron, Timothy D. Mchugh, Treatment Action Group, Tully, Vadwai, Van Rie, van Wyk, Wallis, Walzl, Weyer, Wilson, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Wright, Wright, Zar, Ziad Memish, Zumla, Zumla   +118 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Problematisation and regulation: bodies, risk, and recovery within the context of Neonatal Abstinence Syndrome [PDF]

, 2018
Background Neonatal Abstinence Syndrome (NAS) is an anticipated effect of maternal drug use during pregnancy. Yet it remains a contested area of policy and practice.
Chandler, Amy, Cooper, Sarah, Cunningham-Burley, Sarah, Elliott, Lawrie, Midgley, Paula, Whittaker, Anne   +5 more
core   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source