Results 91 to 100 of about 6,817,458 (407)

Spotlight on Genetic Kidney Diseases: A Call for Drug Delivery and Nanomedicine Solutions [PDF]

open access: hybrid, 2023
Noah Trac   +5 more
openalex   +1 more source

Photoacoustic Drug Delivery

open access: yesSensors, 2017
Photoacoustic (PA) technology holds great potential in clinical translation as a new non-invasive bioimaging modality. In contrast to conventional optical imaging, PA imaging (PAI) enables higher resolution imaging with deeper imaging depth. Besides applications for diagnosis, PA has also been extended to theranostic applications.
Zhang, Yuqi   +3 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Polymer–Lipid Hybrid Nanosystems: An Emerging Advanced Therapeutic Tool

open access: yesAdvances in Polymer Technology
Polymer–lipid hybrid (PLH) nanoparticles have become an appealing therapeutic delivery system owing to their special properties. These nanoparticles are made with polymer and lipid components and have garnered significant interest across therapeutic ...
Nnamdi Ikemefuna Okafor   +3 more
doaj   +1 more source

Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

open access: yesJournal for ImmunoTherapy of Cancer, 2019
Background DNA vaccines against cancer held great promises due to the generation of a specific and long-lasting immune response. However, when used as a single therapy, they are not able to drive the generated immune response into the tumor, because of ...
Alessandra Lopes   +6 more
doaj   +1 more source

Programmable biomaterials for dynamic and responsive drug delivery [PDF]

open access: yes, 2016
Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Head‐to‐head comparison between ACQ and FRET in probing polymeric micelles

open access: yesView
Environmentally responsive fluorophores, such as those with aggregation‐caused quenching (ACQ) and Förster resonance energy transfer (FRET) properties, are widely used to track nanocarriers while minimizing artifacts.
Runtong Zhang   +9 more
doaj   +1 more source

Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate

open access: yesChemistryOpen, 2023
The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties.
Zohre Montaseri   +3 more
doaj   +1 more source

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