Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Preparation of TPM–NCs–gel and its effect on subcutaneous abscess caused by Staphylococcus aureus
Journal of Holistic Integrative PharmacyObjective: The insoluble compound 1,1′-(2,4,6-trihydroxy-1,3-phenylene)bis(3-methylbutan-1-one) (TPM) is used in preparing a TPM nanocrystals gel (TPM–NCs–gel), and its in vitro antibacterial activity and therapeutic effect on subcutaneous abscesses ...
Quanwei Xie +7 more
doaj
Advanced Targeted Drug Delivery for Colon Cancer Using Pristine and Surface-modified Hydroxyapatite Nanoparticles: Synthesis, Characterization, and pH-Responsive Release [PDF]
arXivHydroxyapatite nanoparticles (HANs) have emerged as a promising candidate for targeted drug delivery in the treatment of colon cancer, a disease that remains one of the leading causes of cancer-related deaths globally. In this study, we synthesized and characterized HANs for their potential use as drug delivery vehicle for anticancer drugs specifically
arxiv
Pulsatile Drug Delivery System Based on Electrohydrodynamic Method [PDF]
arXiv, 2012 Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS, plays a significant role in the pulsatile drug delivery system for a decade. In this paper, an EHD based drug delivery system is well designed, which can be used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a total device of 2\times2\times3 mm^3, and an ...
arxiv
Aging and Cancer, EarlyView.ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley +1 more source
Calculation of Droplet Size and Formation Time in Electrohydrodynamic Based Pulsatile Drug Delivery System [PDF]
arXiv, 2012 Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS, plays a significant role in the pulsed-release drug delivery system for a decade. In this paper, an EHD based drug delivery system is well designed, which can be used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a total device of 2x2x3 mm^3, and an external
arxiv
A Revision of the Bernoulli Equation as a Controller of the Fick's Diffusion Equation in Drug Delivery Modeling [PDF]
arXiv, 2019 Mathematical equations can be used as effectual tools in drug delivery systems modeling and are also highly helpful to have a theoretical understanding of controlled drug release and diffusion mechanisms. In this study we aim to present a mathematical combination between the Bernoulli equation and the Fick's equation as a diffusion controller in drug ...
arxiv
, 2019 Recent advances in locoregional chemotherapy have opened the door to new approaches for the clinical management of peritoneal carcinomatosis (PC) by facilitating the delivery of anti-neoplastic agents directly to the tumor site, while mitigating adverse ...
Ceelen, Wim +4 more
core +1 more source
Stable oral availability of sustained release propranolol when co‐ administered with hydralazine or food: evidence implicating substrate delivery rate as a determinant of presystemic drug interactions. [PDF]
, 1984 AJ Byrne +5 more
openalex +1 more source
Remote-Controlled Activation of the Release through Drug-Loaded Magnetic Electrospun Fibers [PDF]
arXivThe integration of magnetic nanoparticles within fibrillar structures represents an interesting avenue for the remotely controlled release of therapeutic agents. This work presents a novel drug release platform based on electrospun magnetic fibers (EMFs) combining drugs, magnetic nanoparticles (MNPs) and mesoporous silica nanoparticles (MSNs) for ...
arxiv