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Chronotherapeutic Drug Delivery

Journal of Infusion Nursing, 2012
Living organisms follow a circadian rhythm in which physiological processes such as hormonal secretion, metabolism, heart rate, and renal output are affected by the time of day. Chronotherapy coordinates drug delivery with the circadian rhythm to enhance effectiveness and mitigate adverse effects and is achieved by delivering a drug when the system is ...
Paul, Librodo   +3 more
openaire   +3 more sources

Optimisation of Drug Delivery: 4. Transdermal Drug Delivery

The Australian Journal of Hospital Pharmacy, 1997
This article reviews the current status and possible future directions for transdermal drug delivery. Skin penetration is briefly discussed and chemical and physical enhancer methods to increase skin penetration are outlined. Design considerations for transdermal drug delivery systems and products available in Australia are reviewed.
Heather AE Benson, Richard J Prankerd
openaire   +3 more sources

Optimisation of Drug Delivery: 5. Pulmonary Drug Delivery

The Australian Journal of Hospital Pharmacy, 1998
This article reviews the origins, current status and possible future directions for drug delivery by the pulmonary route. Deposition of drugs in the lungs is briefly discussed and methods to improve pulmonary bioavailability are outlined. Design aspects of pulmonary drug delivery systems and products available in Australia are reviewed.
Heather AE Benson, Richard J Prankerd
openaire   +3 more sources

Drug Delivery Systems

Pain Practice, 2006
Abstract:  Intrathecal drug delivery (IDD) is a proven and effective treatment alternative in carefully selected patients with chronic pain that cannot be controlled by a well‐tailored drug regime and/or spinal cord stimulation (SCS), and may be specifically trialed in patients who fail to respond to SCS.
Serdar, Erdine, José, De Andrés
openaire   +2 more sources

Drug delivery

Medical Journal of Australia, 2002
What we know: In preschool children, small-volume spacers perform better than large-volume spacers. Detergent is the best antistatic agent for spacers, increasing lung delivery two- to threefold, but it must not be rinsed off. A mouthpiece should be used in children aged 2-3 years or older, as lung delivery is two- to threefold higher for oral ...
openaire   +2 more sources

Iontophoretic drug delivery

Advanced Drug Delivery Reviews, 2004
The composition and architecture of the stratum corneum render it a formidable barrier to the topical and transdermal administration of therapeutic agents. The physicochemical constraints severely limit the number of molecules that can be considered as realistic candidates for transdermal delivery.
Kalia, Yogeshvar   +3 more
openaire   +2 more sources

Drugs in the delivery room

Seminars in Fetal and Neonatal Medicine, 2019
The need for cardiopulmonary resuscitation in newborns is quite rare, as most non-vigorous infants respond well to effective ventilation. For the minority of babies who do not respond to adequate ventilation, chest compressions are necessary using the preferred two thumb technique.
Shalini, Ramachandran, Myra, Wyckoff
openaire   +2 more sources

Spinal drug delivery

Current Pain and Headache Reports, 2001
Clinicians currently base decisions regarding the use of intrathecal drug therapy for chronic pain on reports from uncontrolled and retrospective studies that fail to rely on standardized outcome measures. In this article, we summarize what is known about currently administered intrathecal therapies, including opioids, gamma-aminobutyric acid agonists,
T S, Grabow, D, Derdzinski, P S, Staats
openaire   +2 more sources

Drug Delivery Systems. 6. Transdermal Drug Delivery

The Journal of Clinical Pharmacology, 1991
Transdermal drug delivery system has been in existence for a long time. In the past, the most commonly applied systems were topically applied creams and ointments for dermatological disorders. The occurrence of systemic side‐effects with some of these formulations is indicative of absorption through the skin.
openaire   +2 more sources

Cyclodextrins in drug delivery

Expert Opinion on Drug Delivery, 2005
Cyclodextrins are a family of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic central cavity. Cyclodextrin molecules are relatively large with a number of hydrogen donors and acceptors and, thus, in general they do not permeate lipophilic membranes.
Thorsteinn, Loftsson   +3 more
openaire   +2 more sources

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