Results 31 to 40 of about 1,809,547 (313)

Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy

Drug Delivery, 2022
Based on the tumor hypoxic microenvironment and the new programmed cell death mode of combined ferroptosis, an angelica polysaccharide-based nanocarrier material was synthesized.
Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen, Hongjie Mu   +9 more
doaj   +1 more source

The Smart Drug Delivery System and Its Clinical Potential

Theranostics, 2016
With the unprecedented progresses of biomedical nanotechnology during the past few decades, conventional drug delivery systems (DDSs) have been involved into smart DDSs with stimuli-responsive characteristics.
Dong Liu, Fang Yang, F. Xiong, N. Gu
semanticscholar   +1 more source

Mucoadhesive drug delivery systems

Journal of Pharmacy And Bioallied Sciences, 2011
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for ...
Rahamatullah, Shaikh, Thakur, Raj Singh, Garland, M.J., Woolfson, David, Donnelly, Ryan   +4 more
openaire   +4 more sources

Peptide-Based Drugs and Drug Delivery Systems [PDF]

Molecules, 2017
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Stefania Galdiero, Paula A. C. Gomes
openaire   +4 more sources

Preparation of TPM–NCs–gel and its effect on subcutaneous abscess caused by Staphylococcus aureus

Journal of Holistic Integrative Pharmacy
Objective: The insoluble compound 1,1′-(2,4,6-trihydroxy-1,3-phenylene)bis(3-methylbutan-1-one) (TPM) is used in preparing a TPM nanocrystals gel (TPM–NCs–gel), and its in vitro antibacterial activity and therapeutic effect on subcutaneous abscesses ...
Quanwei Xie, Feirong Zhou, Runan He, Lianbao Ye, Zonghao Lin, Xiangyu Nie, Yuanzheng Wei, Chuqin Yu   +7 more
doaj   +1 more source

Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2017
Emerging evidence suggests that alpha-processing single transmembrane proteins, amyloid precursor protein (APP) and anti-aging protein Klotho, are likely to be involved in the progression of Alzheimer’s disease (AD).
Xi Kuang, Hong-Jing Zhou, Amy H. Thorne, Xi-Nan Chen, Lin-Jiao Li, Jun-Rong Du   +5 more
doaj   +1 more source

Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL−35

Pharmaceutics, 2021
Pharmaceutical excipients (PEs) are substances included in drug formulations. Recent studies have revealed that some PEs can affect the activity of metabolic enzymes and drug transporters; however, the effects of PEs on CYP2C8 and its interaction ...
Chengming Wen, Haoyang Hu, Wenwen Zhang, Xin Liu, Xuehua Jiang, Ling Wang   +5 more
doaj   +1 more source

Liposomal Drug Delivery Systems and Anticancer Drugs [PDF]

Molecules, 2018
Cancer is a life-threatening disease contributing to ~3.4 million deaths worldwide. There are various causes of cancer, such as smoking, being overweight or obese, intake of processed meat, radiation, family history, stress, environmental factors, and chance. The first-line treatment of cancer is the surgical removal of solid tumours, radiation therapy,
Temidayo Olusanya, Rita Haj Ahmad, Daniel Ibegbu, James Smith, Amal Elkordy   +4 more
openaire   +5 more sources

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

Leveraging engineered mitochondria through intercellular communication network for accelerated transport and delivery

Nature Communications
Inspired by the non-transmembrane transfer of mitochondria in cell-to-cell communications, herein, we report an original exploration to accelerate mitochondrial intercellular transport, and its application to exogenous cargo delivery.
Yiwei Peng, Datong Gao, Yiliang Yang, Yitian Du, Zhenzhen Yang, Jiajia Li, Meng Lin, Yanxia Zhou, Xinru Li, Xianrong Qi   +9 more
doaj   +1 more source